Guyton and Hall Textbook of Medical Physiology (Guyton Physiology) 14th
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Edition
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Chapter 01: Functional Organization of the Human Body and Control of the —Internal
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Environment‖
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Hall: Guyton and Hall Textbook of Medical Physiology, 14th Edition
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MULTIPLE CHOICE L
1. Which of the following statements about homeostasis is incorrect?
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a. It refers to the maintenance of a stable internal environment for the body.
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b. Homeostatic mechanisms do not operate in diseases. L L L L L L
c. Homeostasis requires integrated actions of the cells, tissues, organs, and multiple L L L L L L L L L L
nervous, hormonal, and local control systems. L L L L L
d. Homeostatic compensations that begin after a major environmental challenge may
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contribute to abnormalities of body function. L L L L L
ANS: B L
2. What is the most abundant type of cell in the human body?
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a. Neuron
b. Epithelial cell L
c. Red blood cell L L
d. White blood cell L L
e. Vascular smooth muscle cell L L L
f. Skeletal muscle cell L L
ANS: C L
3. The most abundant substance in the human body and the approximate percentage of that
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substance in the body is which of the following?
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a. Protein, 30% L
b. Protein, 60% L
c. Water, 30% L
d. Water, 60% L
e. Carbohydrate, 30% L
f. Carbohydrate, 60% L
ANS: D L
4. If the feedback gain of a control system is
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a. a negative feedback system capable of correcting 1/2 of the initial disturbance to
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the system. L
b. a negative feedback system capable of correcting 2/3 of the initial disturbance to
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the system. L
c. a negative feedback system capable of correcting 3/4 of the initial disturbance to
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, the system. L
d. a positive feedback system capable of correcting 1/2 of the initial disturbance to
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the system. L
e. a positive feedback system capable of correcting 2/3 of the initial disturbance to
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the system. L
f. a positive feedback system capable of correcting 3/4 of the initial disturbance to
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the system. L
ANS: B L
5. Which of the following substances has the highest extracellular fluid to intracellular fluid
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concentration ratio for most mammalian cells?
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a. Sodium ions L
b. Potassium ions L
c. Carbon dioxide L
d. Glucose
e. Protein
ANS: A L
6. Exchange of substances between the cardiovascular system and the interstitial fluid occurs
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Lmainly in which of the following?
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a. Arteries
b. Arterioles
c. Capillaries
d. Venules
e. Veins
ANS: C L
7. What is the approximate distance from the capillaries to most cells of the body?
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a. Less than 50 angstroms L L L
b. Less than 50 microns L L L
c. Less than 50 millimeters L L L
d. Less than 100 angstroms L L L
e. Less than 100 microns L L L
f. Less than 100 millimeters L L L
ANS: A L
8. When a person is at rest, how much time is required for the blood in the circulation to
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Ltraverse the entire circulatory circuit?
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a. 1 second
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b. 1 minute
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c. 3 minutes
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d. 4 minutes
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e. 5 minutes
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ANS: B L
9. The type of control system that can sometimes cause instability and vicious cycles is
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Lcalled
, a. negative feedback. L
b. feed-forward control. L
c. positive feedback. L
d. adaptive feedback. L
e. delayed negative feedback. L L
ANS: C L
10. Which of the following is an example of positive feedback in the body?
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a. Return of blood pressure toward normal after a hemorrhage
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b. Generation of action potentials in nerves L L L L L
c. Increased respiration rate caused by accumulation of carbon dioxide in the blood
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d. Decreased sympathetic nervous system activity that occurs in response to
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increased blood pressure L L
ANS: B L
11. Which of the following is an example of a —feed-forward‖ control system?
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a. The arterial baroreceptor system
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b. The progressive nature of uterine contractions during childbirth
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c. Control of skeletal muscle movements by the brain
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d. Generation of an action potential L L L L
ANS: C L
12. Which of the following is an example of negative feedback?
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Example 1: Arterial baroreceptor control of blood pressure
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Example 2: Excitation of the respiratory center by increased blood carbon dioxide
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concentration
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Example 3: Hemorrhagic shock caused by severe blood loss
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a. Example 1 only L L
b. Example 2 only L L
c. Example 3 only L L
d. Examples 1 and 2, but not 3 L L L L L L
e. Examples 1, 2, and 3 L L L L
ANS: D L
Chapter 02: The Cell and Its Functions
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Hall: Guyton and Hall Textbook of Medical Physiology, 14th Edition
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MULTIPLE CHOICE L
1. The most abundant cell membrane lipids are
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a. sphingolipids.
b. phospholipids.
c. cholesterol.
d. triglycerides.
e. sterols.
, ANS: B L
2. Organelles that neutralize drugs and toxins are
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a. nuclei.
b. mitochondria.
c. lysosomes.
d. peroxisomes.
e. endoplasmic reticulum. L
ANS: D L
3. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Initiation of translation‖ L L
a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum L L
d. Granular endoplasmic reticulum L L
e. Golgi apparatus L
f. Endosomes
g. Peroxisomes
h. Cytosol
ANS: H L
4. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Protein sorting and packaging‖
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a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum L L
d. Granular endoplasmic reticulum L L
e. Golgi apparatus L
f. Endosomes
g. Peroxisomes
h. Lysosomes
ANS: E L
5. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Gene transcription‖
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a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum L L
d. Granular endoplasmic reticulum L L
e. Golgi apparatus L
f. Endosomes
g. Peroxisomes
h. Lysosomes