NR283
Chamberlain University
NR283-12821 Pathophysiology
Week 7: Concept Process Assignment
Guidelines #3 Reflection
Our group had Parkinson's disease as our system disorder. Parkinson's
disease is, according to the NIH, a "brain disorder that leads to shaking,
stiffness, and difficulty with walking, balance, and coordination. Parkinson's
symptoms usually begin gradually and get worse over time. As the disease
progresses, people may have difficulty walking and talking." As a basic
concept, we chose orthostatic hypotension. Orthostatic hypotension is defined
as a form of low blood pressure that happens when standing up from sitting or
lying down. Being that Parkinson's is a neurological disorder. It causes what is
labeled as nOH, meaning neurogenic orthostatic hypotension. nOH is caused
by a failure in the autonomic nervous system to properly stabilize the body's
blood pressure when the body’s position and gravity change. The body's blood
pressure is not being controlled because due to Parkinson's, the body loses the
nerve endings that produce norepinephrine causing an inadequate amount to be
released. This leads to orthostatic hypotension and supine hypertension. Studies
conducted by the NIH show that nOH is common in Parkinson's disease.
It is essential to mention that there is no consistent association between
orthostatic symptoms and finding orthostatic hypotension when the patient's