HLTH 501 WEEK 8 FINAL EXAM
Question 1
10 out of 10 points
Match the Following:
Question Correct Match Selected Match
Bias E. E.
Systematic uncertainty Systematic uncertainty
Double Blind D. D.
Subject and researcher Subject and researcher
unaware of treatment status unaware of treatment status
Clinical Trial J. J.
Subject randomly assigned to Subject randomly assigned to
treatment groups treatment groups
Cohort I. I.
Subjects with common Subjects with common
characteristics followed over characteristics followed over
time time
Confounding A. A.
Risk factor distortion Risk factor distortion
Cross- H. H.
sectional At a single point in time At a single point in time
Disease C. C.
Incidence Number of new case of Number of new case of
disease over time disease over time
Intention to B. B.
treat Do not have to complete Do not have to complete
treatment treatment
Matching F. F.
Creating similar comparison Creating similar comparison
groups groups
Per protocol G. G.
, Followed all treatment/study Followed all treatment/study
procedures procedures
Question 2
10 out of 10 points
A study is planned to assess the effect of a new surgical intervention for
gallbladder disease. One hundred patients with gallbladder disease will be
randomly assigned to receive either the new surgical intervention or the
standard surgical intervention. The efficacy of the new surgical intervention
will be measured by the time is takes a patient to return to normal activities,
measured in days. Identify the type of study proposed and indicate its specific
strengths and weaknesses.
Type of study: (3.3 points)
Strengths: (3.3 points)
Weaknessess: (3.3 points)
Correct Answer: [None]
Question 3
10 out of 10 points
In 1940, 2,000 women working in a factory were recruited into a study. Half of
the women worked in manufacturing and half in administrative offices. The
incidence of bone cancer through 1970 among the 1,000 women working in
manufacturing was compared with that of 1,000 women working in
administrative offices. Thirty of the women in manufacturing developed bone
cancer as compared to 9 of the women in administrative offices. This study is
an example of a:
Correct Answer:
cohort study
Question 4
, 10 out of 10 points
The following are body mass index (BMI) scores measured in 12 patients who
are free of diabetes and participating in a study of risk factors for obesity. Body
mass index is measured as the ratio of weight in kilograms to height in meters
squared. Generate a 95% confidence interval estimate of the true BMI.
25 27 31 33 26 28 38 41 24 32 35 40
Upper limit of CI: (5 points)
Lower Limit of CI: (5 points)
Correct Answer:
Lower limit of CI: 27.95
Upper Limit of CI: 36
Question 5
10 out of 10 points
A clinical trial is conducted to evaluate the effectiveness of a new drug to
prevent preterm delivery. A total of n=250 pregnant women agree to participate
and are randomly assigned to receive either the new drug or a placebo and
followed through the course of pregnancy. Among 125 women receiving the
new drug, 24 deliver preterm and among 125 women receiving the placebo, 38
deliver preterm. Construct a 95% confidence interval for the difference in
proportions of women who deliver preterm.
1. Upper Limit CI= (5 points)
2. Lower Limt CI = (5 points)
Question 1
10 out of 10 points
Match the Following:
Question Correct Match Selected Match
Bias E. E.
Systematic uncertainty Systematic uncertainty
Double Blind D. D.
Subject and researcher Subject and researcher
unaware of treatment status unaware of treatment status
Clinical Trial J. J.
Subject randomly assigned to Subject randomly assigned to
treatment groups treatment groups
Cohort I. I.
Subjects with common Subjects with common
characteristics followed over characteristics followed over
time time
Confounding A. A.
Risk factor distortion Risk factor distortion
Cross- H. H.
sectional At a single point in time At a single point in time
Disease C. C.
Incidence Number of new case of Number of new case of
disease over time disease over time
Intention to B. B.
treat Do not have to complete Do not have to complete
treatment treatment
Matching F. F.
Creating similar comparison Creating similar comparison
groups groups
Per protocol G. G.
, Followed all treatment/study Followed all treatment/study
procedures procedures
Question 2
10 out of 10 points
A study is planned to assess the effect of a new surgical intervention for
gallbladder disease. One hundred patients with gallbladder disease will be
randomly assigned to receive either the new surgical intervention or the
standard surgical intervention. The efficacy of the new surgical intervention
will be measured by the time is takes a patient to return to normal activities,
measured in days. Identify the type of study proposed and indicate its specific
strengths and weaknesses.
Type of study: (3.3 points)
Strengths: (3.3 points)
Weaknessess: (3.3 points)
Correct Answer: [None]
Question 3
10 out of 10 points
In 1940, 2,000 women working in a factory were recruited into a study. Half of
the women worked in manufacturing and half in administrative offices. The
incidence of bone cancer through 1970 among the 1,000 women working in
manufacturing was compared with that of 1,000 women working in
administrative offices. Thirty of the women in manufacturing developed bone
cancer as compared to 9 of the women in administrative offices. This study is
an example of a:
Correct Answer:
cohort study
Question 4
, 10 out of 10 points
The following are body mass index (BMI) scores measured in 12 patients who
are free of diabetes and participating in a study of risk factors for obesity. Body
mass index is measured as the ratio of weight in kilograms to height in meters
squared. Generate a 95% confidence interval estimate of the true BMI.
25 27 31 33 26 28 38 41 24 32 35 40
Upper limit of CI: (5 points)
Lower Limit of CI: (5 points)
Correct Answer:
Lower limit of CI: 27.95
Upper Limit of CI: 36
Question 5
10 out of 10 points
A clinical trial is conducted to evaluate the effectiveness of a new drug to
prevent preterm delivery. A total of n=250 pregnant women agree to participate
and are randomly assigned to receive either the new drug or a placebo and
followed through the course of pregnancy. Among 125 women receiving the
new drug, 24 deliver preterm and among 125 women receiving the placebo, 38
deliver preterm. Construct a 95% confidence interval for the difference in
proportions of women who deliver preterm.
1. Upper Limit CI= (5 points)
2. Lower Limt CI = (5 points)
