BIOS 242 MICROBIOLOGY MIDTERM EXAM
STUDY GUIDE
BIOS242 Midterm Study Guide
This Midterm contributes 150 points to your overall grade, so please do
your best!
There are 36 multiple choice questions worth 3 points each (108 points
total).
There are four matching questions worth 4 points each (16 points
each)
There are two short answer questions worth 8 points each (16 points
total).
There is one essay answer question worth 10 points.
The Midterm covers TCOs 1–8.
Remember to save your answers often.
You have been allotted 2 hours for the Midterm.
Remember to submit your Midterm when you are finished.
1. Given a list of Koch's postulates, analyze how early
microbiologists proposed hypotheses and performed experiments
to determine the causes of various diseases.
1.The suspected causative agent must be found in every case
of the disease and be absent from healthy hosts.
2.The agent must be isolated and grown outside the host.
3.When the agent is introduced to a healthy, susceptible host,
the host must get the disease.
4.The same agent must be found in the diseased experimental
host.
, Key Concepts
Describe the contributions of Leeuwenhoek and Koch to the field
of microbiology.
Anton van Leeuwenhoek (1632 - 1723) was a Dutch tradesman
and scientist, best known for his work on the development and
improvement of the microscope and also for his subsequent
contribution towards the study of microbiology.
Describe how Pasteur used the scientific method to disprove
spontaneous generation.
To disprove the theory of spontaneous generation, Louis Pasteur
devised a way to flask that allowed oxygen in, but prevented
dust from entering. The broth did not show signs of life until he
broke off the neck of the flask allowing dust, and therefore
microbes, to enter.
Describe other historical or current experiments on the cause of
disease.
Today, we understand that infectious diseases like flu,
chickenpox and pneumonia are caused by microscopic
organisms – bacteria and viruses. Without this knowledge,
we might have never developed ways to treat and prevent
such infections. However, this understanding – known as the
‘germ theory’ of disease – was a remarkably recent
discovery.
People have created theories to explain human disease for
millennia: the Greek physician Hippocrates, born in 460
BCE, thought that ‘bad air’ from swampy areas was to
blame. In the 19th century, improvements in microscope
technology enabled a generation of microbiologists to
investigate further the world of previously unseen disease-
causing organisms.
Summarize early research into the prevention of infection.
Examples of infection prevention and control measures at Lake
City Community Hospital include hand hygiene, protective
STUDY GUIDE
BIOS242 Midterm Study Guide
This Midterm contributes 150 points to your overall grade, so please do
your best!
There are 36 multiple choice questions worth 3 points each (108 points
total).
There are four matching questions worth 4 points each (16 points
each)
There are two short answer questions worth 8 points each (16 points
total).
There is one essay answer question worth 10 points.
The Midterm covers TCOs 1–8.
Remember to save your answers often.
You have been allotted 2 hours for the Midterm.
Remember to submit your Midterm when you are finished.
1. Given a list of Koch's postulates, analyze how early
microbiologists proposed hypotheses and performed experiments
to determine the causes of various diseases.
1.The suspected causative agent must be found in every case
of the disease and be absent from healthy hosts.
2.The agent must be isolated and grown outside the host.
3.When the agent is introduced to a healthy, susceptible host,
the host must get the disease.
4.The same agent must be found in the diseased experimental
host.
, Key Concepts
Describe the contributions of Leeuwenhoek and Koch to the field
of microbiology.
Anton van Leeuwenhoek (1632 - 1723) was a Dutch tradesman
and scientist, best known for his work on the development and
improvement of the microscope and also for his subsequent
contribution towards the study of microbiology.
Describe how Pasteur used the scientific method to disprove
spontaneous generation.
To disprove the theory of spontaneous generation, Louis Pasteur
devised a way to flask that allowed oxygen in, but prevented
dust from entering. The broth did not show signs of life until he
broke off the neck of the flask allowing dust, and therefore
microbes, to enter.
Describe other historical or current experiments on the cause of
disease.
Today, we understand that infectious diseases like flu,
chickenpox and pneumonia are caused by microscopic
organisms – bacteria and viruses. Without this knowledge,
we might have never developed ways to treat and prevent
such infections. However, this understanding – known as the
‘germ theory’ of disease – was a remarkably recent
discovery.
People have created theories to explain human disease for
millennia: the Greek physician Hippocrates, born in 460
BCE, thought that ‘bad air’ from swampy areas was to
blame. In the 19th century, improvements in microscope
technology enabled a generation of microbiologists to
investigate further the world of previously unseen disease-
causing organisms.
Summarize early research into the prevention of infection.
Examples of infection prevention and control measures at Lake
City Community Hospital include hand hygiene, protective
