Bad Fish Case
1. Present the “Doctors Notes” portion of the case with a description
of the following terms or concepts:
● Diaphoresis - Excessive sweating, side effect to pill
● Motor Dysfunction - Nervous system isn’t responding
● Paresthesias - Damaged Peripheral nerves
● Cyanotic - Skin Discoloration
● Hypoventilating- Slower breathing, and more CO2
● Bradycardia - Slower heart reaction
● Gastric Lavage- Forced excessive excretion/ vomiting
● Oxygen Saturation- Percentage of oxygen in the blood
2. How many different elements are contained in a molecule of
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tetrodotoxin? What are the names of these elements?
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Tetrodotoxin are contained with Hydrogen, Nitrogen, Carbon, and
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Oxygen.
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3. What type of chemical bonds are found in the molecule? Describe the
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structures of these bonds.
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These are called covalent bonds which share electrons.
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4. As mentioned in the case description, tetrodotoxin is a molecule that
blocks voltage-gated sodium ion channels. Describe the structure of a
sodium ion?
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A sodium Ion is smaller than a sodium atom
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5. What is a voltage- gated sodium ion channel? What is it made of? What
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is its function?
It's a gate that lets certain Ions through, it is made of protein. When
one lets a little bit of Sodium it triggers a reaction throughout the gated
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Ion channels, and floods the sodium to the nerve.
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6. As mentioned in the case description, tetrodotoxin is a molecule that
blocks voltage-gated sodium ion channels. Describe the structure of a
sodium ion
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The sodium can't get through the cell membrane
7. Describe the process involved in the movement of ions through these
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channels
When it's at resting state it is more negative on the inside then on
the outside. Then when it reaches a point -55 in which it opens the sodium
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Ion channels. After that happens then the inside becomes more positive
than the outside. Next sodium potassium channels open up pumps K+ out.
Then back to normal.
8. When nerve cells are at rest, there is an unequal amount of positive and
negative charges on either side of a nerve cell membrane. This charge
difference is called an electrical potential. Describe this “potential” when
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