PHARMACOLOGY EXAM 1 STUDY GUIDE(Download for excellent Scores)

PHARMACOLOGY EXAM 1 STUDY GUIDE • Drugs that PRODUCE a response? • Drugs that PREVENT a response? • Therapeutic WINDOW is what? • The time it takes for ½ of the drug concentration to be eliminated from the body is called? • What is a patient on two highly protein bound drugs at risk for • What is it called for drugs to share many common features • What makes drugs fit into the same “class” • Another name for antagonist? • Who do you not give antagonist or adrenergic blocker to? • Beta blockers commonly seen in what clients? • Antagonist suffix • Antagonist S/S • Agonist S/S • Before administering antagonist what do you check • Cholinergic • Anticholinergic • What type of drug is Reglan? • How do you treat cholinergic crisis • Cholinergic crisis S/S • Anticholinergic drugs are contraindicated in who? • CNS stimulant drugs are contraindicated in who? • Hemorrhagic stroke • Anorexiants can lead to what? • Most common side effects of Ritalin o Irritability o Insomnia ▪ Weight loss ▪ Decrease appetite • Benzodiazepines increase activity to what neurotransmitter (PAM & LAM) o GABA • Reversal to benzodiazepines o Flumazenil • Ambien side effects o Sedative/hypnotic o Suicidal ideation o Dependence o Abnormal behavior • Drug choice for treating status epilepticus o Diazepam’s • Dilantin can do what? o Cause gum disease o Treat seizures o Cause high BP o Cause birth defects o Decrease effectiveness of anticoagulants • When a client is on Dilantin what are some nursing interventions? o Monitor for narrow therapeutic index (freq blood test) o Take as prescribed o Oral care o Teach pt to use barrier contraceptives along with oral • What is therapeutic level for Depakote? o 40-100 • If Depakote levels are high (100) what needs to be done? o Hold meds o Check liver function with blood test o Discuss with DR o Neuro assessment o Check vitals • What does Depakote treat? o Epilepsy o Migraine • Bipolar disorder • Benzodiazepines can lead to what? o Tolerance o Dependence o Withdrawal • Barbiturates reversal treatment o Activated charcoal • Example of barbiturates o Phenobarbital • What disease process goes with “dopamine depletion”, rigidity, acetylcholine accumulation, acetylocholinerase inhibitor drugs, facial masking, motor neuron degeneration and anticholinergic drugs o Parkinson’s disease • What disease goes with confusion, bradykinesia, memory loss, amyloid plaques, and neurofibrillary tangles o Alzheimer’s disease • Aricept improves what? o Cholinergic function • What is SLUD o Salivation, lacrimation, urination, defecation • You CANNOT crush CONTIN, POTASSIUM and IRON o You CAN crush calcium antacids