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Blood

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Introduction to Blood

Institution
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4 1
ummm
Blood
Overview of Blood circulation
Blood leaves the heart via arteries that branchrepeatedly until theybecome capillaries

Oz r nutrients diffuseacross capillarywalls enter tissues

cozywastes move from tissues intothe blood
O2 deficient blood leaves the capillaries oflows in viens to the heart

Blood flows to the longs where it releases coz r picks up 02

02 rich blood returns to the heart


Composition of blood
Blood is the only fluid tissue
Made up of liquidplasma's formed elements

Formed elements include Erthocytes red blood cells RBCs
Leukocytes white blood cells WBCs
Platelets
Hematocrit of RBCs out of total blood volume 454 in healthy people



components of whole blood

,Physical characteristics r Volume

Blood is sticky opaque fluid metallic taste due to iron

bright oxygenated red dark deoxygenated red

pH 7.35 7.45 slightly alkaline
38 C

Avg volume i 5 6L formales 4 52 for females males are bigger than female

Accounts for 8 of bodyweight


Functions of Blood
of functions i

1 Substance distribution

Ozfrom the longs ornutrients from the digestive tract
Metabolic wastes from cells to the lungs or kidneys for elimination

Horomones from endocrine glands to target organs
2 Regulation of blood levels of particular substances
Regulatebody temp by absorbing 2 distributing heat shiveringto warm

pH in body tissues using buffer systems bicarbonate ions
Fluid volume in circulatory system osmotic pressure
3 Body protection Hemostasis
Prevents blood loss by i
Activating plasma protients z platelets

Initiating clotformation when a vessel is broken
Prevents infection by i
Synthesizing r utilizing antibodies

, Activating complement proteins

Activating WBCs to defend the body against foreign invaders


Blood Plasma liquid component
Contains over 100 solutes includingi almost all made byliver

Proteins albumin d B gglobulin clottingproteins others

Lacticacid urea creatinine

Organic nutrients glucose carbohydrates aminoacids

Electrolytes sodium potassium calcium chloride bicarbonate

Respiratory gases oxygen or carbondioxide



Formed Elements

Erythrocytes leukocytes andplatelets make up formed elements

Only WBCs are complete cells true cells
RBCs have no nuclei or organelles platelets are
just cell fragments
Most formedelements survive in the blood stream foronly a few days

Most blood cells donot divide bot are renewed by cells in bone marrow



Erythrocytes RBCs
Biconcave discs anucleate no nucleus noorganelles

Major factor contributing to blood viscosity make blood more viscous
Filled with hemoglobin a protein that functions in gas transport

Contain plasma membrane protein spectrin r otherprotiens that

give RBCs their flexibility r allow them to change shape

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Uploaded on
August 3, 2021
Number of pages
20
Written in
2020/2021
Type
Class notes
Professor(s)
John copeland and william staines
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All classes

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