Gallbladder Disease
Gallbladderfunction
causesruin
Gallstone Pathogenesis
Liverproduces bite This
inraunaia
cholesterolphospholipids bilesalts Cholesterol Bile stasis MHaemolysis
waterandconjugatedbilirubin supersaturation
W Dueto Lackof stimulus to ARBCbreakdownlead
storedand concentrated a Aplasmaoestrogen OBemptying toA bilepigment
wigallbladderCOB Female
o women
e g TPN
Forty 340410 Fasting
Lipid rich food in duodenum Fat Bmi 30
Stimulates CCK release Fair Caucasian Cholesterol Mixed Pigment
Fertile 51 child 204 75 5
GB contracts in response FHx usually 1 multiple multiple
to CCK Oralcontraceptive pill shone shores stores
d b Depletion of bile Large 2Scm Different small
Bilepassesinto duodenum via acid pool less smoothand shape and irregulars
Ampulla of Vata fordigestion abuilyforcholesterol onecolour sizes andfragile
of fats to be suspended generations
OHIO
eg Terminalileumresection
Symptoms onlyin 1 4 CdEnterohepanecirculations
or Crohn'sdisease ONLY10 RADIOPAQUE VISIBLEONXR
561 present with BILIARYCOLIC
when store is in neck of GB or cystic On examination
duct unremarkable
Pain is sudden snap RUQIepigastric ieChore
lithiasis Apyrexia
pain that can radiate to R shoulder USS
usually more constant pain with Apain Presence of stores
aftereatingcespfattyrood when CCK Management
causes gall bladdercontraction Analgesia
Op cholecystectomy if pain
36 present with ACUTE CHOLECYSTITIS No Jaundice bothering
asCBDnot patientenough
store lodged in neck of Odo cysticduct
if blocked
f
with Aconcentrated and irritant bile On examination
can involve ascending infection from the Tender RUQ tl guarding14 C
gut E Coa or Klebsiella cholestasisallows
ve Murphy'ssign
constant RUQIepigastric pain that persists
quoresorptionUSS bloods
Nausea and vomiting Enlarged GB w stores and
thickened Walt
Murphy'ssign MCRP Awcc midlyPASTALT ALP
thyagaraja
ManaffggesetinaeYNBM
Nabx
momentaryrespiratory cholecystectomy WITHIN 1 WEEK
depression
bideally 72 hours
Gallbladderfunction
causesruin
Gallstone Pathogenesis
Liverproduces bite This
inraunaia
cholesterolphospholipids bilesalts Cholesterol Bile stasis MHaemolysis
waterandconjugatedbilirubin supersaturation
W Dueto Lackof stimulus to ARBCbreakdownlead
storedand concentrated a Aplasmaoestrogen OBemptying toA bilepigment
wigallbladderCOB Female
o women
e g TPN
Forty 340410 Fasting
Lipid rich food in duodenum Fat Bmi 30
Stimulates CCK release Fair Caucasian Cholesterol Mixed Pigment
Fertile 51 child 204 75 5
GB contracts in response FHx usually 1 multiple multiple
to CCK Oralcontraceptive pill shone shores stores
d b Depletion of bile Large 2Scm Different small
Bilepassesinto duodenum via acid pool less smoothand shape and irregulars
Ampulla of Vata fordigestion abuilyforcholesterol onecolour sizes andfragile
of fats to be suspended generations
OHIO
eg Terminalileumresection
Symptoms onlyin 1 4 CdEnterohepanecirculations
or Crohn'sdisease ONLY10 RADIOPAQUE VISIBLEONXR
561 present with BILIARYCOLIC
when store is in neck of GB or cystic On examination
duct unremarkable
Pain is sudden snap RUQIepigastric ieChore
lithiasis Apyrexia
pain that can radiate to R shoulder USS
usually more constant pain with Apain Presence of stores
aftereatingcespfattyrood when CCK Management
causes gall bladdercontraction Analgesia
Op cholecystectomy if pain
36 present with ACUTE CHOLECYSTITIS No Jaundice bothering
asCBDnot patientenough
store lodged in neck of Odo cysticduct
if blocked
f
with Aconcentrated and irritant bile On examination
can involve ascending infection from the Tender RUQ tl guarding14 C
gut E Coa or Klebsiella cholestasisallows
ve Murphy'ssign
constant RUQIepigastric pain that persists
quoresorptionUSS bloods
Nausea and vomiting Enlarged GB w stores and
thickened Walt
Murphy'ssign MCRP Awcc midlyPASTALT ALP
thyagaraja
ManaffggesetinaeYNBM
Nabx
momentaryrespiratory cholecystectomy WITHIN 1 WEEK
depression
bideally 72 hours
