HP 320 GLOBAL HEALTH QUIZZES

HP 320 GLOBAL HEALTH QUIZZESHP 320 GLOBAL HEALTH QUIZZES Issues in study design quiz Score for this module: 100% 1. A protocol coming before an REC has received scientific review. When reviewing the protocol the REC identifies additional scientific issues relatin… o may require that amendments are made to the study design if the scientific issues identified by the committee have ethical implications Your correct answer o may require changes to the study design, even if the scientific issues identified do not have implications for the ethics of the research. o should not take scientific issues without ethical implications into account when reviewing the ethics of a particular research protocol Your correct answer o all of the above 2. Which of the following are examples of issues relating to research design which may have ethical implications: (select all that apply) o A protocol for a quantitative study with a proposed sample size that is too small to give statistically significant results Your correct answer o A protocol that uses methods and endpoints designed to prove that treatment A is better than treatment B, rather than the evaluate whether treatment A is better than treatment B Your correct answer o A protocol where the proposed methods cannot generate the data needed to answer the research question Your correct answer o A protocol using a high risk methodology designed to deliver definitive results rapidly, where alternatives which pose less risk to participants are available Your correct answer 3. The choice of a placebo as a comparator in research when an established effective intervention exists is controversial. o True Your correct answer o False 4. Which of the following are examples of deception in research? (select all that apply) o protocols may seek to deceive participants about the nature of the research (e.g. a study to monitor protocol compliance) Your correct answer o protocols may seek to enrol participants who are unaware that they are taking part in research (i.e. submission of a dummy protocol to multiple RECs to study outcomes) Your correct answer 5. When considering if the proposed sample size for a study has ethical implications, an REC may wish to consider: o how many potential participants could meet the inclusion criteria and if there are other studies seeking to access, or currently being conducted with, these participant