What is conjugate acid-base pairs? The stronger the acid, the weaker the base.
Such pairs are termed as conjugate acid base
pairs. Cl- is the conjugate base of the acid HCL.
What do you mean by aprotes? The cations such as Na+, Ca+2, K+, Mg+2
cannot donate or accept protons. Hence they
are neither acids nor bases. Such cations are
called aprotes.
Mention the factors involved in the regulation 1) Buffer systems of blood
of blood ph 2) Respiratory Mechanisms
3) Renal Mechanisms
4) Dilution factor
How is H2SO4 produced in the body? This acid is formed by the oxidation of sulphur
containing amino acids in the body e.g-
methionine and cystine
Why is NaHCO3 in the blood represented as Because it does NOT combine with strong and
the alkali reserve? non volatile acids
What is the disadvantage of Bicarbonate This buffer is a very weak chemical buffer and
Buffer? hence its pKa is far from the physiological pH
Prove that the Phosphate Buffer system works 1) When a strong acid enters the blood, it
in conjunction with the kidneys. is fixed up by Na2HPO4 which is
converted to acid phosphate. This acid
phosphate is excreted by the kidneys
showing that the urine becomes more
acidic.
2) When an alkali enters it is buffered by
acid phosphate forming the alkaline
phosphate which is excreted in the
urine showing the increased alkalinity
of urine.
Show the effects of imidazole group of Imidazole contains 2 groups:
histidine on the physiological buffering action
1) Fe2+ containing group which is
of Hb.
concerned with the carriage of O2
2) Imidazole N2 group which can give up
H+ and accept H+ depending on the pH
of the medium.
What do you mean by isohydric transport of The newly formed H+ in tissues from H2CO3
CO2? does not bring a change in pH. This
circumstance in the role of Hb buffers is
sometimes referred to as isohydric transport of
Such pairs are termed as conjugate acid base
pairs. Cl- is the conjugate base of the acid HCL.
What do you mean by aprotes? The cations such as Na+, Ca+2, K+, Mg+2
cannot donate or accept protons. Hence they
are neither acids nor bases. Such cations are
called aprotes.
Mention the factors involved in the regulation 1) Buffer systems of blood
of blood ph 2) Respiratory Mechanisms
3) Renal Mechanisms
4) Dilution factor
How is H2SO4 produced in the body? This acid is formed by the oxidation of sulphur
containing amino acids in the body e.g-
methionine and cystine
Why is NaHCO3 in the blood represented as Because it does NOT combine with strong and
the alkali reserve? non volatile acids
What is the disadvantage of Bicarbonate This buffer is a very weak chemical buffer and
Buffer? hence its pKa is far from the physiological pH
Prove that the Phosphate Buffer system works 1) When a strong acid enters the blood, it
in conjunction with the kidneys. is fixed up by Na2HPO4 which is
converted to acid phosphate. This acid
phosphate is excreted by the kidneys
showing that the urine becomes more
acidic.
2) When an alkali enters it is buffered by
acid phosphate forming the alkaline
phosphate which is excreted in the
urine showing the increased alkalinity
of urine.
Show the effects of imidazole group of Imidazole contains 2 groups:
histidine on the physiological buffering action
1) Fe2+ containing group which is
of Hb.
concerned with the carriage of O2
2) Imidazole N2 group which can give up
H+ and accept H+ depending on the pH
of the medium.
What do you mean by isohydric transport of The newly formed H+ in tissues from H2CO3
CO2? does not bring a change in pH. This
circumstance in the role of Hb buffers is
sometimes referred to as isohydric transport of
