Borrelia
Introduction:
They are larger than other spirochetes, with 3-10 irregular wide and open coils.
They are motile, refractile, spirochetes.
Commensal of buccal and genital mucosa.
Stained by ordinary dye and gram negative.
PATHOGEN MORPHOLOGY CULTURE ANTIGENIC PATHOGENESIS LAB.DIAGNOSIS TREATMENT/
STRUCTURE PROPHYLAXIX
B.recurrentis. Gram negative, Microaerophilic, Undergoes Transmitted by: body louse & Specimen: blood. PET/ control of
(relapsing motile, possess 28-30°C antigenic tick. Dark field vector.
fever) 5-8 irregular Grown on: variation in vivo Onset of febrile microscopy.
B.duttoni. spirals Noguchi’s which cause episode( borrelia in blood), Geimsa/leishman
Stains: médium, CAM, replaces of subsides 3-5days. Afebrile last stain.
geimsa/Wright. peritoneal cavity disease. for 4-10 days and relapses Animal
of rat or mouse occurs. Speelnogamy. inoculation.
Serology is
difficult.
B.vincentii. Gram negative, Cultivation is B.vincentii is Under mal-nutrition or viral Specimen :lesion PM
(vincent’s Motile, 3-8 difficult but can ofetn infection , causes ulcerative excudate.
angina) coils. be done in associated with gingivostomatitis or Staining.
Stains: dilute enriched media fusiform bacilli oropharyngitis.
carbol fuchsin, anaerobically. (fusobacterium
methyl violet. fusiforme)
B.burgdorferi Gram negative, Microaerophilic. Midgut of tick, transmission: Specimen: skin PET.
(lyme disease) flexible and 33-37°C. regurgitation. lesions, CSF, blood.
Natural host: helical fastidious. 1. localisied lesions: Culture is too slow
rodent, deer, Grown on : BSK erythema migrans. and difficult.
mammals. medium.( 2 2. Disseminated infection: ELISA, IF FTA-ABS.
Vector: ixodid weeks or more) headache,fever,myalgia
tick. and lymphadenopathy.
3. Persistent infection:
Introduction:
They are larger than other spirochetes, with 3-10 irregular wide and open coils.
They are motile, refractile, spirochetes.
Commensal of buccal and genital mucosa.
Stained by ordinary dye and gram negative.
PATHOGEN MORPHOLOGY CULTURE ANTIGENIC PATHOGENESIS LAB.DIAGNOSIS TREATMENT/
STRUCTURE PROPHYLAXIX
B.recurrentis. Gram negative, Microaerophilic, Undergoes Transmitted by: body louse & Specimen: blood. PET/ control of
(relapsing motile, possess 28-30°C antigenic tick. Dark field vector.
fever) 5-8 irregular Grown on: variation in vivo Onset of febrile microscopy.
B.duttoni. spirals Noguchi’s which cause episode( borrelia in blood), Geimsa/leishman
Stains: médium, CAM, replaces of subsides 3-5days. Afebrile last stain.
geimsa/Wright. peritoneal cavity disease. for 4-10 days and relapses Animal
of rat or mouse occurs. Speelnogamy. inoculation.
Serology is
difficult.
B.vincentii. Gram negative, Cultivation is B.vincentii is Under mal-nutrition or viral Specimen :lesion PM
(vincent’s Motile, 3-8 difficult but can ofetn infection , causes ulcerative excudate.
angina) coils. be done in associated with gingivostomatitis or Staining.
Stains: dilute enriched media fusiform bacilli oropharyngitis.
carbol fuchsin, anaerobically. (fusobacterium
methyl violet. fusiforme)
B.burgdorferi Gram negative, Microaerophilic. Midgut of tick, transmission: Specimen: skin PET.
(lyme disease) flexible and 33-37°C. regurgitation. lesions, CSF, blood.
Natural host: helical fastidious. 1. localisied lesions: Culture is too slow
rodent, deer, Grown on : BSK erythema migrans. and difficult.
mammals. medium.( 2 2. Disseminated infection: ELISA, IF FTA-ABS.
Vector: ixodid weeks or more) headache,fever,myalgia
tick. and lymphadenopathy.
3. Persistent infection:
