Module 10 -#30
1. Scleroderma
a. AKA systemic sclerosis
b. Rare autoimmune connective tissue disorder
c. Abnormal thickening of the skin
d. Secondary Raynaud’s phenomenon can occur
2. Lupus
a. 2 classifications:
i. Discoid (affects the skin)
ii. Systemic (causes major body organs to fail) (has remission and exacerbations, causes direct
damage and causes vasculitis which deprives organ of blood and oxygen) (Butterfly rash across
the nose, nephritis, pericarditis, Raynaud’s phenomenon)
b. Lupus nephritis is the leading cause of death for lupus because of the damage done to the kidneys
3. Rheumatoid arthritis
a. Autoimmune inflammatory systemic disease of the synovial joints. CD4+ helper cells stimulate release of
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cytokine release, stimulates neutrophils to break down cartilage. Steroids
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4. CREST Syndrome
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a. Multisystem connective tissue disorder
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b. Calcinosis
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c. Raynaud’s phenomenon
d. Esophageal dysfunction
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e. Sclerodactyly (thickening and tightening of skin of fingers and hands)
f. Telangiectasia (dilation of capillaries, red marks on surface on skin)
5. Reynaud’s
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a. Think of Elsa from Frozen (cold hands and feet); can’t get a pulse Ox because fingers are too cold
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b. Risk factors for primary Reynaud’s: sex, age, climate, family history
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c. Secondary Reynaud’s: happens as a result of another illness
6. Osteoarthritis
a. Most common type of arthritis in the U.S.
b. Results in bone rubbing against bone in the joint space causing joint pain and stiffness leading to
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decreased mobility and muscle atrophy
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c. Risk Factors: aging, genetic factor, obesity, trauma, occupation
d. Treatments: NSAIDS, acetaminophen, other analgesics
7. Gout
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a. Systemic disease where urate crystals deposit in the joints and other body tissues
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b. Primary: inborn errors of purine metabolism with the end product uric acid
c. Secondary gout hyperurcemia caused by another disease or factor
d. Risk Factors: obesity, cardiovascular disease, alcohol, chronic kidney failure, starvation/dieting, trauma
e. Education: avoid organ (red meats) or shellfish, limit alcohol intake, limit aspirins, and diuretics, remind
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pt to increase fluid intake
f. Treatments: NSAIDs, corticosteroids, main medication= colchicine
8. Fibromyalgia
a. Chronic Pain Syndrome
b. Widespread musculoskeletal pain w fatigue, sleep, memory and mood issues
c. Cause is unknown
d. Risk dactors: sex (more prevalent in women than men), family history, more likely to develop if you have
osteoarthritis, lupus, RH
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, e. Treatment: none
9. Priority care
10. Patient education
Module 9 -#30
1. Infection types
a. Opportunistic: infections caused by non-pathogenic microorganisms which becomes pathogenic when
the immune system is impaired by an unrelated disease(Think of a person with HIV –chronic stage of a
disease- getting a infectious disease like pneumonia
b. Pathogenic:
2. Immunity types
a. Antibody-mediated immunity-humoral immunity
i. Antigen-antibody interactions to neutralize, destroy, or eliminate foreign proteins; antibodies are
produced by sensitized B-lymphocytes; the antibodies are produced by the lymphocytes and
destroy the invading protein; B-cells are produced in the spleen, lymph nodes, tonsils and
mucosa of the intestinal tract
b. Cell-mediated immunity-cellular immunity
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i. Rely on the function of the T-cells as well as the cells known as natural killer cells; natural killer
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cells are known as CD16+ cells and have a direct effect of non-self-cells without first being
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sensitized, they also seek and destroy abnormal self-cells such as cancer cells and virally infected
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body cells
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3. Prevention of infection
a. Avoid crowds
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b. Bathe daily with antimicrobial soap
c. Wash hands thoroughly
d. Avoid raw fruits and vegetables
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e. Avoid working in the garden or with houseplants
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f. Monitor for signs and symptoms of infection
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i. Increase in temperature
ii. Purulent drainage
iii. Foul-smelling drainage
iv. Cloudy urine
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4. HIV patient psychosocial
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a. Depression, suicidal ideas, body dysmorphia
5. AIDS findings of infection
a. Fever, fatigue, headache, rash, sore throat, swollen lymph nodes, monitor intake, educate client about
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medications (if they have any symptoms of TB then they must be quarantined immediately in an air tight
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room)
6. Sterile field
a. Area created by placing sterile drapes around the patient’s surgical site and on the stand that will hold
sterile instruments and other items needed during surgery
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7. Impaired immune system
a. HIV patients, post-op patients, cancer patients
8. Skin protection
a. Sunblock, skin moisturizer, skin barriers
9. Antibiotics
a.
10. Virulence
a. Power of the agent to cause a disease and the ability to damage its host
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