1. Immunohistochemistry – Enumerate and Define the different Tumor Markers
Enzyme Tumor Markers
Tumor Marker Tumor Type Specimen Method Clinical Utility
Prostate- Prostate Serum Immunoassay Prostate cancer
specific Cancer screening, therapy
antigen monitoring, and
recurrence.
Lactate Hematologic Serum Enzyme assay Prognostic
dehydrogenase malignancies indicator, elevated
nonspecifically in
numerous cancers
Alkaline Metastatic Serum Enzyme assay Determination of
phosphatase carcinoma of the liver and bone
bone, involvement;
hepatocellular Nonspecific
carcinoma, elevation in many
osteosarcoma, bone-related and
Leukemia liver cancers
Neuron- Neuroendocrine Serum Radioimmunoassay Prognostic
specific tumors Immunohistochemistry indicator and
enolase monitoring
disease
progression for
neuroendocrine
tumors
Enzyme Tumor Markers
Tumor Marker Tumor Type Specimen Method Clinical Utility
Prostate- Prostate Serum Immunoassay Prostate cancer
specific Cancer screening, therapy
antigen monitoring, and
recurrence.
Lactate Hematologic Serum Enzyme assay Prognostic
dehydrogenase malignancies indicator, elevated
nonspecifically in
numerous cancers
Alkaline Metastatic Serum Enzyme assay Determination of
phosphatase carcinoma of the liver and bone
bone, involvement;
hepatocellular Nonspecific
carcinoma, elevation in many
osteosarcoma, bone-related and
Leukemia liver cancers
Neuron- Neuroendocrine Serum Radioimmunoassay Prognostic
specific tumors Immunohistochemistry indicator and
enolase monitoring
disease
progression for
neuroendocrine
tumors
