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Biological Macromolecules Lecture Notes

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BIOLOGICAL MACROMOLECULES

CARBOHYDRATES

 Carbohydrates are one of the macromolecules which contain carbon, hydrogen and oxygen only with a ratio
1:2:1.This can be written as CnH2nOn, where n corresponds to the number of carbon atoms. The term
carbohydrate comes from the Latin word saccharum which means sugar.
 Carbohydrates are classified either as simple or complex. Simple sugars are monosaccharides and disaccharides.
Complex sugars are polysaccharides.
 Carbohydrates are the primary energy source of the human body. The different saccharides that humans eat are
converted to glucose which can be readily used by the body. Around 4 kilocalories is derived from one gram of
carbohydrate. Should there be an excessive consumption of carbohydrates, the excess is converted to glycogen
which is stored in the liver and in muscles. Glycogen is a slow-releasing carbohydrate.

MONOSACCHARIDE (ONE SACCHARIDE)

Glucose

 Used in dextrose, blood sugar; the form utilized by the human body

Galactose

 Found in milk and milk products

Fructose

 Found in fruits and honey

DISACCHARIDE (TWO SACCHARIDES)

Maltose

 Glucose + Glucose
 Found in malt

Sucrose

 Glucose + Fructose
 Found in regular table sugar, sugarcane, and sugar beet

Lactose

 Glucose + Galactose
 Found in milk and milk products

Individual saccharides are connected via glycosidic bonds. A water molecule is released when two saccharides are
combined.

POLYSACCHARIDE (MANY SACCHARIDES)

Starch / Amylose

 Composed of 250 - 400 glucose molecules connected via α-1-4- glycosidic bond.
 Storage form of glucose in plants

Amylopectin

 Like amylose but has more branches attached via α-1-6 glycosidic bond
 Storage form of glucose in plants

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