lOMoARcPSD|3013804
Focus Nursing Pharmacology 7th Karch Test
Bank
Introduction to the New Testament (New York University)
, lOMoARcPSD|3013804
FOCUS ON NURSING PHARMACOLOGY
7TH EDITION KARCH TEST BANK
TEST BANK
, lOMoARcPSD|3013804
FOCUS ON NURSING PHARMACOLOGY 7TH EDITION KARCH TEST
Test Bank - Focus on Nursing Pharmacology (7th Edition by Amy Karch) 1
Chapter 02- Drugs and the Body
1. Drugs do not metabolize the same way in all people. For what patient would a nurse expect to
assess for an alteration in drug metabolism?
A) A 35-year-old woman with cervical cancer
B) A 41-year-old man with kidney stones
C) A 50-year-old man with cirrhosis of the liver
D) A 62-year-old woman in acute renal failure Ans:
C
Feedback:
The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as
in patients with cirrhosis, drugs will not metabolize normally so that toxic levels could develop
unless dosage is reduced. A patient with cervical cancer or kidney stones would not be expected to
have
altered ability to metabolize drugs so l o n g a s n o l i v e r d a m a g e existed. The patient with renal
failure would have altered excretionNofUtheR drugs
S I Nthrough
G T Bthe
. Crenal
O Msystem but metabolism would not
be
impacted.
2. A patient presents to the emergency department with a drug level of 50 units/mL. The half-life of
this drug is 1 hour. With this drug, concentrations above 25 units/mL are considered toxic and no more
drug is given. How long will it take for the blood level to reach the non-toxic range?
A) 30 minutes
B) 1 hour
C) 2 hours
D) 3 hours
Ans: B
Feedback:
Half-life is the time required for the serum concentration of a drug to decrease by 50%. After 1
hour, the serum concentration would be 25 units/mL (50/2) if the body can properly metabolize and
excrete the drug. After 2 hours, the serum concentration would be 12.5 units/mL (25/2) and reach the
nontoxic range. In 30 minutes the drug level would be 37.5 units/mL, whereas in 3 hours the drug
level would be
Focus Nursing Pharmacology 7th Karch Test
Bank
Introduction to the New Testament (New York University)
, lOMoARcPSD|3013804
FOCUS ON NURSING PHARMACOLOGY
7TH EDITION KARCH TEST BANK
TEST BANK
, lOMoARcPSD|3013804
FOCUS ON NURSING PHARMACOLOGY 7TH EDITION KARCH TEST
Test Bank - Focus on Nursing Pharmacology (7th Edition by Amy Karch) 1
Chapter 02- Drugs and the Body
1. Drugs do not metabolize the same way in all people. For what patient would a nurse expect to
assess for an alteration in drug metabolism?
A) A 35-year-old woman with cervical cancer
B) A 41-year-old man with kidney stones
C) A 50-year-old man with cirrhosis of the liver
D) A 62-year-old woman in acute renal failure Ans:
C
Feedback:
The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as
in patients with cirrhosis, drugs will not metabolize normally so that toxic levels could develop
unless dosage is reduced. A patient with cervical cancer or kidney stones would not be expected to
have
altered ability to metabolize drugs so l o n g a s n o l i v e r d a m a g e existed. The patient with renal
failure would have altered excretionNofUtheR drugs
S I Nthrough
G T Bthe
. Crenal
O Msystem but metabolism would not
be
impacted.
2. A patient presents to the emergency department with a drug level of 50 units/mL. The half-life of
this drug is 1 hour. With this drug, concentrations above 25 units/mL are considered toxic and no more
drug is given. How long will it take for the blood level to reach the non-toxic range?
A) 30 minutes
B) 1 hour
C) 2 hours
D) 3 hours
Ans: B
Feedback:
Half-life is the time required for the serum concentration of a drug to decrease by 50%. After 1
hour, the serum concentration would be 25 units/mL (50/2) if the body can properly metabolize and
excrete the drug. After 2 hours, the serum concentration would be 12.5 units/mL (25/2) and reach the
nontoxic range. In 30 minutes the drug level would be 37.5 units/mL, whereas in 3 hours the drug
level would be
