Pathophysiology Chapter 04 - Genes and Genetic Diseases

Pathophysiology Chapter 04 - Genes and Genetic Diseases



1. In somatic cell gene therapy, what type of vector is most commonly used to alter a specific

set of an individual’s somatic cells?

a. Virus

b. Bacteria

c. RNA polymerase

d. Recombinant DNA

2. In DNA replication, what does the enzyme DNA polymerase do?

a. Travel along the single DNA strand, adding the correct nucleotide to the new strand

b. Move along the double strand of DNA to unwind the nucleotides of the double helix

c. Hold the double strand apart while the correct nucleotides are added to the strand

d. Transport the double strand of DNA from the nucleus to the cytoplasm for protein

formation

3. How is transcription best defined?

a. DNA polymerase binds to the promoter site on ribonucleic acid (RNA).

b. RNA directs the synthesis of polypeptides for protein synthesis.

c. RNA is synthesized from a DNA template.

d. A base pair substitution results in a mutation of the amino acid sequence.

4. What is the purpose of using a Giemsa staining technique on chromosomes?

a. Permit the mitotic process to be followed and monitored for variations.

b. Allow for the numbering of chromosomes and the identification of variations.

c. Identify new somatic cells formed through mitosis and cytokinesis.

d. Distinguish the sex chromosomes from the homologous chromosomes.