Pathophysiology Chapter 06 - Epigenetics and Disease
1. What genetic process is likely responsible for the occurrence of asthma in only one of a
pair of identical twins?
a. Epigenetic modifications
b. Genomic imprinting
c. Transgenerational inheritance
d. Methylation
2. Prader-Willi syndrome causes a chromosomal defect that is what?
a. Initiated by postnatal exposure to a virus
b. Inherited from the father
c. Related to maternal alcohol abuse
d. Transferred from mother to child
3. What can a malfunction in DNA methylation lead to?
a. Hypothyroidism
b. Blindness
c. Cancer
d. Diabetes mellitus
4. Which statement is true regarding the embryonic development of stem cells?
a. They are already differentiated.
b. They are referred to as housekeeping genes.
c. They already demonstrate DNA sequencing.
d. They are said to be totipotent.
5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are
over- expressed. What would be the resulting effect on existing cancer?
1. What genetic process is likely responsible for the occurrence of asthma in only one of a
pair of identical twins?
a. Epigenetic modifications
b. Genomic imprinting
c. Transgenerational inheritance
d. Methylation
2. Prader-Willi syndrome causes a chromosomal defect that is what?
a. Initiated by postnatal exposure to a virus
b. Inherited from the father
c. Related to maternal alcohol abuse
d. Transferred from mother to child
3. What can a malfunction in DNA methylation lead to?
a. Hypothyroidism
b. Blindness
c. Cancer
d. Diabetes mellitus
4. Which statement is true regarding the embryonic development of stem cells?
a. They are already differentiated.
b. They are referred to as housekeeping genes.
c. They already demonstrate DNA sequencing.
d. They are said to be totipotent.
5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are
over- expressed. What would be the resulting effect on existing cancer?
