NR293 HESI STUDY GUIDE

•Protein bound •Reason for giving Nitro sublingually – eliminates first pass effect, under the tongue is very vascular •Half life – the amount of time it takes for half of the drug to be excreted out of the body •Kinetic phases of pharmacology oAbsorption oDistribution oMetabolism oExcretion •Pro-drug – given in active form, does not have to be metabolized in the liver •Polypharmacy – many drugs 5-6 given at once oCauses problems •Opioids given around the clock – palliative care – control symptoms and pain •Neonatal drug metabolism – decreased gastric acid, the liver is not fully developed, at risk for toxicity •1st antihypertensive given – thiazide diuretic •Culture – must be culturally competent and take into consideration other cultures beliefs oi.e. Hispanics – go to folk healer •Autonomy – own decision •Beneficence •Veracity – honesty •Justice – fairness for all •New diagnosis of HTN start low dose – can always increase, gives room to “play around” •Prophylaxis – give before and after procedure as prevention •Penicillin and Cephalosporins are “cousins” do not give a cephalosporins if the patient has an allergy to pens (and vice- versa) because of the beta lactam ring similarities •Tetracycline – photosensitivity, no sun, no tanning beds