NURSING NUR2407LPharmacology Exam #2 Study Guide

Pharmacology Exam #2 [Unit 7: Pain and Inflammation Management Drugs]  Nonsteroidal Antiinflammatory Drugs (NSAIDS): o Aspirin (ASA)- (Salicylates)  used to reduce pain and inflammation symptoms, decreased fever, and inhibit platelet aggregation; for osteoarthritis and rheumatoid arthritis  Side Effects:  Dizziness  Drowsiness  loss of appetite (anorexia)  nausea and vomiting  diarrhea  heartburn  abdominal pain  rash  Adverse Reactions:  Tinnitus  hearing loss  G.I. ulceration and bleeding  Life Threatening:  hemolytic anemia  bronchospasm  anaphylaxis  hepatotoxicity  Drug Interaction:  increased risk of bleeding with anticoagulants and other NSAIDs  increased risk of hypoglycemia with oral hypoglycemic drugs  effects are decreased by corticosteroids  increased ulcerogenecid effect with glucocorticoids  Contraindications:  hypersensitivity to salicylates or NSAIDs  flu or virus symptoms in children  G.I. bleeding  Caution: renal or hepatic disorders, gout, alcoholism, anticoagulant therapy, G.I. bleeding, bone marrow suppression, head trauma, immunosuppression, pregnancy.  Anemia  Measles  Chicken Pox  Reye Syndrome  Decreased prothrombin levels (clotting factor)  Salicylate Poisoning:  tinnitus (ringing in ears)  elevated temperature  nausea and vomiting  dehydration