1. Azithromycin dosing requires that the first day’s dosage be twice those of the
other 4 days of the prescription. This is considered a loading dose. A loading dose:
Rapidly achieves drug levels in the therapeutic range
Requires four- to five-half-lives to attain
Is influenced by renal function
Is directly related to the drug circulating to the target tissues
2. Patient education for a patient who is prescribed antibiotics for sinusitis
includes:
Use of nasal saline washes
Use of inhaled corticosteroids
Avoiding the use of ibuprofen while ill
Use of laxatives to treat constipation
3. A client asks the NP about the differences in drug effects between men and
women. What is known about the differences between the pharmacokinetics of
men and women?
Body temperature varies between men and women.
Muscle mass is greater in women.
Percentage of fat differs between genders.
Proven subjective factors exist between the genders.
4. The drug of choice for type 2 diabetics is metformin. Metformin:
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Increases intestinal uptake of glucose
Prevents weight gain associated with hyperglycemia