Professional Nursing I (Rasmussen University)
, Study Guide Exam 3
Things to know and review:
Chapter 41: Immunity
Immune System has three duties:
• Defend the body from invaders
• Identify body's cells and monitor for any neoplasms (tumor cells)
• Maintaining homeostasis by removing cellular waste
Innate (Natural): Immunity that is present at birth and develops regardless of exposure.
Acquired (adaptive or specific): Immunity that is not present and develops as a result of
exposure or through an external source, such as immunization.
• Adaptive immune responses are either humoral-mediated or cell-mediated.
o Humoral is mediated by B lymphocytes, plasma cells, and antibodies.
o Cell-mediated is mediated by T lymphocytes.
Immunogen: Any molecule that can initiate an immune response. Such as, viruses, bacteria,
pollen, toxins, foods, transplanted organs, or transfused blood.
1) The difference between allergic reaction and sensitivity
• Allergic reaction causes an immune response and sensitivity does not.
2) What is a hyper, or exaggerated immune response, suppressed immune response,
allergic reaction, anaphylactic reaction?
• Suppressed immune responses are referred to as immunocompromised or
immunodeficiency.
o Primary immunodeficiency is a group of disorders caused by inherited or genetic
defects in the cells and tissues of the immune system.
o Secondary immunodeficiency occurs when the immune system is compromised
due to an environmental factor; such as cancer, AIDS, and infections.
• Exaggerated responses are referred to as hypersensitive.
o Involves activation of IgE bound to mast cells, with release of histamine.
o Symptoms include bronchospasm, wheezing, rhinorrhea, and urticarial to
angioedema, and finally anaphylaxis.
• Allergic reaction: Immune response reacts abnormally to a foreign substance.
• Anaphylaxis: A more severe, potentially life-threatening allergic reaction.
3) What are characteristics of inflammation?
• Localized pain
• Redness
• Heat