BIO 12317.2_hormonal_communication_ms A_level ocr biology

1

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Hormonol
communication
Mark Scheme 2

Level A Level
SubjectBiology
Exam Board OCR
TopicCommunication, homeostasis and energy
Sub-Topic Hormonal communication
BookletMark Scheme 2




Time Allowed: 64 minutes

Score: / 53

Percentage: /100




Grade Boundaries:

A* A B C D E U

>85% 77.5% 70% 62.5% 57.5% 45% <45%

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Question Answer Marks Guidance
1 (a) ( 1 idea of maintaining (relatively) stable internal , 1 Need the idea of ‘constant’ or ‘steady’
environment / and ‘regulation’ or ‘keeping’
state ; and in the body

2 ACCEPT about the ‘norm’
2 within (narrow) limits / within (narrow) range /
about a set
point ;

3 even though environment is changing ; IGNORE ref to negative feedback (as mechanism
rather than definition) / optimum conditions

CREDIT mps 2 & 3 (only) if response is in
terms of example(s) e.g. temperature /
blood glucose

Note
‘maintaining a stable body temperature’ = 0
‘keeping your body temperature at 37oC’ = 1
2 max (mp 2) ‘even though it is getting cold’ = 1

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Question Answer Marks Guidance
1 (a) (i 1  cells /  cells / receptors , detect , 1 CREDIT correct ref to detection by /a (low) or /b (high)
change / increased / decreased , IGNORE monitor / stimulate / figures quoted
in blood glucose
(concentration) ;
2 CCEPT ‘produce’ rather than release
2 if high(er) glucose (concentration) , DO NOT CREDIT B cells
beta /  , cells (in pancreas) release
insulin ; 3 CREDIT increased permeability of named cell to glucose
IGNORE ‘use’ / target cell
3 (increased) uptake / absorption , of glucose by ,
liver / muscle / effector , 4 CREDI GLUT channels
cells ;

4 enters through glucose transport proteins 5 unambiguous spelling only of glycogen and glycogenesis
(in cell surface
6 DO NOT CREDIT in context of  and  cells
membrane) ;
ACCEPT ‘increased respiration by body’
5 glucose converted to glycogen / glycogenesis ;
7 unambiguous spelling only of
6 increased (use of glucose in) , respiration / ATP production glucagon
; ACCEPT ‘produce’ rather than release

8 unambiguous spelling only of glycogen and glycogenolysis
7 if low(er) glucose (concentration) ,
alpha /  , (in pancreas) cells release 9 unambiguous spelling only of gluconeogenesis
glucagon ;

8 (increased) conversion of glycogen to glucose /
glycogenolysis ;
11 e.g. correct cellular detail for insulin release or in effector
9 (increased) conversion of other compounds cells …
(amino acids / lipids) to glucose / gluconeogenesis ; ● insulin binds to receptor on plasma membrane of
hepatocytes
10 glucose leaves cells , 5 max
●correct ref to secondary messenger (cAMP)
by facilitated diffusion / through glucose channels ; 1 e.g. ref to inhibitory effect(s) of hormone …
●conversion in cells / secretion of antagonist
11 AVP ;
Use of three terms from:
receptor, beta, insulin,
effector, glycogen, glycogenesis,
alpha, glucagon, glycogenolysis,
QWC – technical terms used appropriately and spelt correctly ; gluconeogenesis, facilitated diffusion
Please insert a QWC symbol next to the pencil icon, followed
by
a tick ()🗸 if QWC has been awarded
or a cross ()🗴 if QWC has not been awarded
You should use the green dot to identify the QWC terms that you are
crediting.