1. Activation of the classical pathway begins with:
a. Viruses c. Mast cells
b. Antigen-antibody complexes d. Macrophages
2. The chemotactic factor affects the inflammatory process by:
a. Causing vasodilation around the inflamed area
b. Stimulating smooth muscle contraction in the inflamed area
c. Directing leukocytes to the inflamed area
d. Producing edema around the inflamed area
3. In the later stages of an inflammatory response, which phagocytic cell is predominant?
a. Neutrophils c. Chemokines
b. Monocytes d. Eosinophils
4. Which cell is the body’s primary defense against parasite invasion?
a. Eosinophil c. T lymphocytes
b. Neutrophils d. B lymphocytes
5. Which characteristic is the most important determinant of immunogenicity when considering
the antigen?
a. Size c. Complexity
b. Foreignness d. Quantity
6. The B-cell receptor (BCR) complex functions uniquely by:
a. Communicating information about the antigen to the helper T cell
b. Secreting chemical signals to communicate between cells
c. Recognizing the antigen on the surface of the B lymphocyte
d. Communicating information about the antigen to the cell nucleus
7. Which is an example of an endogenous antigen?
a. Yeast c. Bacteria
b. Cancer cells d. Fungus
8. When a person is exposed to most antigens, antibodies can be usually detected in his or her
circulation within:
a. 12 hours c. 3 days
b. 24 hours d. 6 days
9. Why is the herpes virus inaccessible to antibodies after the initial infection?
a. The virus does not circulate in the blood.
b. It does not have antibody receptors.
c. It resists agglutination.
d. The virus is a soluble antigen.
10. Which is an example of a bacterial toxin that has been inactivated but still retains its
immunogenicity to protect the person? (Select all that apply.)
a. Poliomyelitis
b. Measles
c. Tetanus
d. Gonorrhea
e. Diphtheria
, 11. Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to:
a. Immune complexes that are deposited in capillary beds, blocking circulation
b. Mast cells that are bound to specific endothelial receptors, causing them to
degranulate and creating a localized inflammatory reaction that occludes capillary
circulation
c. Cytotoxic T cells that attack and destroy the capillaries so that they are unable to
perfuse local tissues
d. Antibodies that detect the capillaries as foreign protein and destroy them using
lysosomal enzymes and toxic oxygen species
12. In which primary immune deficiency is there a partial-to-complete absence of T-cell
immunity?
a. Bruton disease c. Reticular dysgenesis
b. DiGeorge syndrome d. Adenosine deaminase deficiency
13. Raynaud phenomenon is an example of which type of hypersensitivity?
a. IV c. II
b. III d. I
14. Which statement is true regarding immunodeficiency?
a. Immunodeficiency is generally not present in other family members.
b. Immunodeficiency is never acquired; rather, it is congenital.
c. Immunodeficiency is almost immediately symptomatic.
d. Immunodeficiency is a result of a postnatal mutation.
15. What is the role of reverse transcriptase in HIV infection?
a. Reverse transcriptase converts single-stranded DNA into double-stranded DNA.
b. It is needed to produce integrase.
c. It transports the RNA into the cell nucleus.
d. It converts RNA into double-stranded DNA.
6. What is a long-term complication of rewarming as a treatment for hypothermia?
a. Acidosis c. Shock
b. Dysrhythmias d. Renal failure
17. Using a fan to reduce body temperature is an example of which mechanism of heat loss?
a. Evaporation c. Convection
b. Radiation d. Conduction
18. Prolonged high environmental temperatures that produce dehydration, decreased plasma
volumes, hypotension, decreased cardiac output, and tachycardia cause which disorder of
temperature regulation?
a. Heat cramps c. Malignant hyperthermia
b. Heat stroke d. Heat exhaustion
19. Heat exhaustion results in: (Select all that apply.)
a. Profuse sweating
b. Profound vasodilation
c. A need to ingest warm liquids
d. Permanent damage to the hypothalamus
e. An increased risk for future heat exhaustion
20. The existence of regular, deep, and rapid respirations after a severe closed head injury is
indicative of neurologic injury to the:
a. Lower midbrain c. Supratentorial