Question 1
6 out of 6 points
Match these infectious agents and inflammatory conditions with the specific cancer
types they commonly cause;
Question Correct Match Selected Match
AIDS
3. 3.
Non-Hodgkin's Non-Hodgkin's
Lymphoma Lymphoma
Asbestosis
4. 4.
Lung cancer Lung cancer
Gingivitis
1. 1.
Oral cancer Oral cancer
Inflammatory Bowel
2. 2.
Disease Colorectal cancer Colorectal cancer
Question 2
0 out of 1 points
In adoptive immunotherapy for melanoma, tumor-infiltrated lymphocytes(TILs) are
expanded ex-vivo then reinfused into the patient together with IL-2. The rationale for the
administration of IL-2 is that it serves as a growth factor for the TILs.
Selected
Answer: False
Correct
Tru
Answer:
e
Question 3
1 out of 1 points
Which of these describes the advantage of DNA antigen-specific vaccines?
Selected
Answer:
They contain multiple epitopes from the
same antigen
Correct
Answer:
They contain multiple epitopes from the
same antigen
Question 4
0 out of 2 points
A drug that inhibits the binding of CTLA-4 to CD86 will help in immunotherapy for
malignant melanoma because it effectively blocks T cell activation.
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:48:33 GMT -06:00
https://www.coursehero.com/file/62845920/BIOM-500-Quiz-6-docx/
, Selected
Answer: True
Correct
Fals
Answer:
e
Question 5
6 out of 6 points
Match these cells of the lymphoid lineage with their appropriate functions in
tumorigenesis;
Question Correct Match Selected Match
Natural killer
B. B.
cells Detect and kill tumor cells through Detect and kill tumor cells through
"missing self" activation or stress- "missing self" activation or stress-
induced activation induced activation
TREG Cell
C. C.
Suppress immunosurveillance but Suppress immunosurveillance but
associated with improved survival associated with improved survival
of patients in multiple cancer of patients in multiple cancer
types types
CD8+
A. A.
Cytotoxic T Recognize and destroy cancer Recognize and destroy cancer
cells cells using perforin and granzyme- cells using perforin and granzyme-
mediated apoptosis mediated apoptosis
CD4+
D. D.
Helper T Secrete anti-inflammatory Secrete anti-inflammatory
cells Type 2 cytokines and are protumorigenic. cytokines and are protumorigenic.
(TH2)
Question 6
1 out of 1 points
Which of these is not a disadvantage of autologous whole-tumor vaccines?
Selected
Answer:
They stimulate neutralizing
antibodies
Correct
Answer:
They stimulate neutralizing
antibodies
Question 7
4 out of 5 points
Match these immune regulatory molecules with their functions in tumorigenesis;
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:48:33 GMT -06:00
https://www.coursehero.com/file/62845920/BIOM-500-Quiz-6-docx/
6 out of 6 points
Match these infectious agents and inflammatory conditions with the specific cancer
types they commonly cause;
Question Correct Match Selected Match
AIDS
3. 3.
Non-Hodgkin's Non-Hodgkin's
Lymphoma Lymphoma
Asbestosis
4. 4.
Lung cancer Lung cancer
Gingivitis
1. 1.
Oral cancer Oral cancer
Inflammatory Bowel
2. 2.
Disease Colorectal cancer Colorectal cancer
Question 2
0 out of 1 points
In adoptive immunotherapy for melanoma, tumor-infiltrated lymphocytes(TILs) are
expanded ex-vivo then reinfused into the patient together with IL-2. The rationale for the
administration of IL-2 is that it serves as a growth factor for the TILs.
Selected
Answer: False
Correct
Tru
Answer:
e
Question 3
1 out of 1 points
Which of these describes the advantage of DNA antigen-specific vaccines?
Selected
Answer:
They contain multiple epitopes from the
same antigen
Correct
Answer:
They contain multiple epitopes from the
same antigen
Question 4
0 out of 2 points
A drug that inhibits the binding of CTLA-4 to CD86 will help in immunotherapy for
malignant melanoma because it effectively blocks T cell activation.
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:48:33 GMT -06:00
https://www.coursehero.com/file/62845920/BIOM-500-Quiz-6-docx/
, Selected
Answer: True
Correct
Fals
Answer:
e
Question 5
6 out of 6 points
Match these cells of the lymphoid lineage with their appropriate functions in
tumorigenesis;
Question Correct Match Selected Match
Natural killer
B. B.
cells Detect and kill tumor cells through Detect and kill tumor cells through
"missing self" activation or stress- "missing self" activation or stress-
induced activation induced activation
TREG Cell
C. C.
Suppress immunosurveillance but Suppress immunosurveillance but
associated with improved survival associated with improved survival
of patients in multiple cancer of patients in multiple cancer
types types
CD8+
A. A.
Cytotoxic T Recognize and destroy cancer Recognize and destroy cancer
cells cells using perforin and granzyme- cells using perforin and granzyme-
mediated apoptosis mediated apoptosis
CD4+
D. D.
Helper T Secrete anti-inflammatory Secrete anti-inflammatory
cells Type 2 cytokines and are protumorigenic. cytokines and are protumorigenic.
(TH2)
Question 6
1 out of 1 points
Which of these is not a disadvantage of autologous whole-tumor vaccines?
Selected
Answer:
They stimulate neutralizing
antibodies
Correct
Answer:
They stimulate neutralizing
antibodies
Question 7
4 out of 5 points
Match these immune regulatory molecules with their functions in tumorigenesis;
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:48:33 GMT -06:00
https://www.coursehero.com/file/62845920/BIOM-500-Quiz-6-docx/
