BIOM 500
Question 1
2 out of 2 points
This drug exerts its anticancer effects by inhibiting the enzyme - dihydrofolate reductase
thereby depleting the cellular folate pool and inhibiting de novo purine synthesis;
Selected
Answer:
Methotrexa
te
Correct
Answer:
Methotrexa
te
Question 2
1.5 out of 1.5 points
You are evaluating apatient with a cancer type that is characterized by constitutive
expression of NFϏB - which promotes oncogenesis, Bortezomib will be most effective in
managing the patient.
Selected
Answer: True
Correct
Tru
Answer:
e
Question 3
2 out of 2 points
This therapeutic target is involved in DNA repair and works by inserting double-stranded
breaks in DNA;
Selected
Answer:
Topoisomerase
II
Correct
Answer:
Topoisomerase
II
Question 4
1 out of 1 points
Match these chemotherapeutic agents to their plant sources;
Question Correct Match Selected Match
Irinoteca
A. A.
n Chinese Yew Tree Chinese Yew Tree
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:52:43 GMT -06:00
https://www.coursehero.com/file/62846065/BIOM-500-Quiz-7-docx/
, Paclitaxel
B. B.
Pacific Yew Tree Pacific Yew Tree
(Bark) (Bark)
Vinblasti
C. C.
ne Pink Periwinkle Pink Periwinkle
Question 5
2 out of 2 points
The functionalmodality of an anantibodythat is composed of VL + CL and VH + CH1 is the;
Selected
Answer:
Fragment of antigen
binding
Correct
Answer:
Fragment of antigen
binding
Question 6
2 out of 2 points
Which of these agents targets the tyrosine kinase domain of the fusion protein formed
from the Philadelphia chromosome and will be helpful in chronic myelogenous leukemia?
Selected
Answer:
Imatini
b
Correct
Answer:
Imatini
b
Question 7
2 out of 2 points
The most commonly used Ig isotype used in cancer immunotherapy is;
Selected
Answer:
IgG
Correct
Answer:
IgG
Question 8
2 out of 2 points
Which of these is not true about Bispecific T-cell Engagers?
Selected
Answer:
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:52:43 GMT -06:00
https://www.coursehero.com/file/62846065/BIOM-500-Quiz-7-docx/
Question 1
2 out of 2 points
This drug exerts its anticancer effects by inhibiting the enzyme - dihydrofolate reductase
thereby depleting the cellular folate pool and inhibiting de novo purine synthesis;
Selected
Answer:
Methotrexa
te
Correct
Answer:
Methotrexa
te
Question 2
1.5 out of 1.5 points
You are evaluating apatient with a cancer type that is characterized by constitutive
expression of NFϏB - which promotes oncogenesis, Bortezomib will be most effective in
managing the patient.
Selected
Answer: True
Correct
Tru
Answer:
e
Question 3
2 out of 2 points
This therapeutic target is involved in DNA repair and works by inserting double-stranded
breaks in DNA;
Selected
Answer:
Topoisomerase
II
Correct
Answer:
Topoisomerase
II
Question 4
1 out of 1 points
Match these chemotherapeutic agents to their plant sources;
Question Correct Match Selected Match
Irinoteca
A. A.
n Chinese Yew Tree Chinese Yew Tree
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:52:43 GMT -06:00
https://www.coursehero.com/file/62846065/BIOM-500-Quiz-7-docx/
, Paclitaxel
B. B.
Pacific Yew Tree Pacific Yew Tree
(Bark) (Bark)
Vinblasti
C. C.
ne Pink Periwinkle Pink Periwinkle
Question 5
2 out of 2 points
The functionalmodality of an anantibodythat is composed of VL + CL and VH + CH1 is the;
Selected
Answer:
Fragment of antigen
binding
Correct
Answer:
Fragment of antigen
binding
Question 6
2 out of 2 points
Which of these agents targets the tyrosine kinase domain of the fusion protein formed
from the Philadelphia chromosome and will be helpful in chronic myelogenous leukemia?
Selected
Answer:
Imatini
b
Correct
Answer:
Imatini
b
Question 7
2 out of 2 points
The most commonly used Ig isotype used in cancer immunotherapy is;
Selected
Answer:
IgG
Correct
Answer:
IgG
Question 8
2 out of 2 points
Which of these is not true about Bispecific T-cell Engagers?
Selected
Answer:
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:52:43 GMT -06:00
https://www.coursehero.com/file/62846065/BIOM-500-Quiz-7-docx/
