BIOM 500
Question 1
2 out of 2 points
Cell cycle-specific anticancer drugs require less frequent dosing/administration in order
to prevent tumor resistance.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 2
2 out of 2 points
Anticancer drugs are highly distributed into cancer cells because of the increased
capacity of these cancer cells for angiogenesis.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 3
0 out of 2 points
Hematolymphoid cells express large numbers of MDR1 and ABCG2 making them highly
sensitive to chemotherapeutic drugs.
Selected
Answer: True
Correct
Fals
Answer:
e
Question 4
2 out of 2 points
Increased tumor heterogenicty increases the likelihood for chemoresistance in tumors.
Selected
Answer: True
Correct
Tru
Answer:
e
Question 5
2 out of 2 points
A possible mechanism of tumor resistance to Methotrexate is the increased expression
of reduced folate carriers by the tumor cells.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 6
2 out of 2 points
Folate deficiency in a cancer patient being treated with 5-Fluorouracil will lead to
diminished capacity of this drug to inhibit thymidylatesynthase.
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:57:30 GMT -06:00
https://www.coursehero.com/file/62845790/BIOM-500-Quiz-8-docx/
, Selected
Answer: True
Correct
Tru
Answer:
e
Question 7
0 out of 2 points
Increased expression of the p53 gene in a cancer patient will result in increased rate
of apoptosis following chemotheray.
Selected
Answer: True
Correct
Fals
Answer:
e
Question 8
2 out of 2 points
You are evaluating a 55 year old breast cancer patient who has been
on Raloxifene and Pertuzumab for the past year, which of these features do you think is
least indicative of tumor resistance?
Selected
Answer:
Tumor regression and remission after
therapy
Correct
Answer:
Tumor regression and remission after
therapy
Question 9
2 out of 2 points
In which of these malignancies do you think that chemotherapy has been the least
successful in producing tumor remission?
Selected
Answer:
Beast
Cancer
Correct
Answer:
Beast
Cancer
Question 10
2 out of 2 points
Which of these physiologic mechanisms of drug resistance is overcome by
the intrathecal administration of chemotherapeutic agents in leukemia?
Selected
Answer:
Drug Sanctuary
sites
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:57:30 GMT -06:00
https://www.coursehero.com/file/62845790/BIOM-500-Quiz-8-docx/
Question 1
2 out of 2 points
Cell cycle-specific anticancer drugs require less frequent dosing/administration in order
to prevent tumor resistance.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 2
2 out of 2 points
Anticancer drugs are highly distributed into cancer cells because of the increased
capacity of these cancer cells for angiogenesis.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 3
0 out of 2 points
Hematolymphoid cells express large numbers of MDR1 and ABCG2 making them highly
sensitive to chemotherapeutic drugs.
Selected
Answer: True
Correct
Fals
Answer:
e
Question 4
2 out of 2 points
Increased tumor heterogenicty increases the likelihood for chemoresistance in tumors.
Selected
Answer: True
Correct
Tru
Answer:
e
Question 5
2 out of 2 points
A possible mechanism of tumor resistance to Methotrexate is the increased expression
of reduced folate carriers by the tumor cells.
Selected
Answer: False
Correct
Fals
Answer:
e
Question 6
2 out of 2 points
Folate deficiency in a cancer patient being treated with 5-Fluorouracil will lead to
diminished capacity of this drug to inhibit thymidylatesynthase.
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:57:30 GMT -06:00
https://www.coursehero.com/file/62845790/BIOM-500-Quiz-8-docx/
, Selected
Answer: True
Correct
Tru
Answer:
e
Question 7
0 out of 2 points
Increased expression of the p53 gene in a cancer patient will result in increased rate
of apoptosis following chemotheray.
Selected
Answer: True
Correct
Fals
Answer:
e
Question 8
2 out of 2 points
You are evaluating a 55 year old breast cancer patient who has been
on Raloxifene and Pertuzumab for the past year, which of these features do you think is
least indicative of tumor resistance?
Selected
Answer:
Tumor regression and remission after
therapy
Correct
Answer:
Tumor regression and remission after
therapy
Question 9
2 out of 2 points
In which of these malignancies do you think that chemotherapy has been the least
successful in producing tumor remission?
Selected
Answer:
Beast
Cancer
Correct
Answer:
Beast
Cancer
Question 10
2 out of 2 points
Which of these physiologic mechanisms of drug resistance is overcome by
the intrathecal administration of chemotherapeutic agents in leukemia?
Selected
Answer:
Drug Sanctuary
sites
This study source was downloaded by 100000830772748 from CourseHero.com on 01-23-2022 03:57:30 GMT -06:00
https://www.coursehero.com/file/62845790/BIOM-500-Quiz-8-docx/
