Migraines – what foods might be a trigger? Migraine and seizure get Arul too. Take beta blocker daily.
- Foods with yeast - Nuts
- MSG - Artificial sweeteners
- Nitrates (meats), marinated foods - Smoked fish
- Pickled / fermented foods
✓ Chocolate, Cheese, yogurt ,Caffeine, nicotine, ice cream, alcohol, stress, fatigue
✓ Lunch/cured meat, hot dogs, smoked meats, Vinegar, Onions
✓ Caffeine, nicotine, ice cream, alcohol, stress, fatigue
Mechanism of action for ergotamine? Use for migraine
Contraindicated with coronary
- Ergotamine selectively binds and activates serotonin (5-HT) 1D receptors located on intracranial blood vessels,
including those on arterio-venous anastomoses, thereby resulting in vasoconstriction and reducing the blood flow in
cerebral arteries that may lead to relieve of vascular headaches.
- Ergotamine has a complex mechanism of action that involves a variety of receptors, including 5-HT-1B/1D, dopamine,
and alpha-adrenoreceptors. By activating 5HT-1B and 5HT-1D receptors on intracranial blood vessels, ergotamine induces
vasoconstriction and relief of migraine headaches.
- Ergotamine also inhibits norepinephrine uptake and stimulates alpha-adrenergic receptors at therapeutic doses, leading to
prolonged vasoconstriction.
S/S of Parkinson’s? Guillain-Barre? With GB what are they most at risk for?? What will kill them first?
Parkinson’s Guillain – Barre paralysis(distal to proximal)
- Falls (require sx carry risk infection, Heart failure - Motor Manifestations: exposure to zika virus
and blood clots and immobility and PNA, - Risk for infection with campylobacter
- Tremors (upper extremities first, worsen with (bacteria un-cook poultry) Influenzas virus.
stress)^ fatigue, slow movement cytomegalovirus
- Change in handwriting • Ascending symmetric muscle weakness
- “Freezing” / stuck to floor • /ascendingFlaccid paralysis without
- Rigidity(rigor). Loss of movement(Akinesia) atrophy
- Resistance to PROM • Decreased / absent DTRs
Cogwheel • Respiratory compromise suction HOB 45
- Rhythmic interruption of movement degree. Paralysis of the muscle of lung,
Plastic blood infection, clot in lungs, or cardiac
- Mildly restrictive movement arrest
Lead pipe • B&B incontinence
- Total resistance to movement • Ataxia
- Masklike face with wide open, fixed eyes
- Uncontrollable drooling - Sensory Manifestations:
• Parasthesias
- Excessive perspiration
• Pain (cramping)
- Orthostatic hypotension
Cranial nerve Manifestations:
- Speech changes: Bradykinesia – slowness of
• Facial weakness
voluntary movement and speech
• Dysphagia
• Speak softly. Med only treat the symptoms
• Diplopia
• Slur / repeat words
• Difficulty speaking
• Monotone voice
• Halting speech
- Autonomic Manifestations:
- B&B incontinence
• Labile BP
- postural instability. • Cardiac dysrhythmias / tachycardia
, What condition closely resembles a stroke but isn’t? migraine, seizure, Hypoglycemia, Bell Pals