WEEK 5 PROBLEMS—30 POINTS
10 points per problem. Place answer in the following table:
1. A. 3.306
B. 4.394
2. A. 438.51
B. 501.41
C. 425.84
3. A. 2.23
B. 1.85
1. A study is run to estimate the association between exposure to lead paint in childhood and
attention-deficit hyperactivity disorder (ADHD). Data on n = 400 children are collected and data
on exposure and ADHD diagnosis are shown below.
Exposure to Lead Paint ADHD No ADHD
Yes 34 71
No 29 266
A. Estimate the crude or unadjusted relative risk.
34/105= .324
29/295= .098. =3.306
B. Estimate the crude or unadjusted odds ratio.
.324/(1-.324)= .479
.098/(1-.098)= .109. =4.394
2. A study is conducted in patients with HIV. The primary outcome is CD4 cell count which is a
measure of the stage of the disease. Lower CD4 counts are associated with more advanced
disease. The investigators are interested in the association between vitamin and mineral
supplements and CD4 count. A multiple regression analysis is performed relating CD4 count to
use of supplements (coded as 1=yes, 0=no) and to duration of HIV, in years (i.e., the number of
years between the diagnosis of HIV and the study date). For the analysis, Y=CD4 count.
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