Test Bank for Basic Pharmacology for Nurses 17th Edition
Test Bank for Basic Pharmacology for Nurses 17th Edition by Bruce Clayton and
Michelle Willinganz
Chapter 02: Basic Principles of Drug Action and Drug
Interactions
Clayton/Willihnganz: Basic Pharmacology for Nurses, 17th Edition
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is
the nurse‟s priority action?
a.Notify physician of allergic reaction.
b.Notify physician of idiosyncratic reaction.
c.Notify physician of potential teratogenicity.
d.Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives
and/or urticaria, which are easily identified. An idiosyncratic reaction occurs when
something unusual or abnormal happens when a drug is first administered. A
teratogenic reaction refers to the occurrence of birth defects related to
,Test Bank for Basic Pharmacology for Nurses 17th Edition
administration of the drug. Tolerance refers to the body‟s requirement for
increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: Page 17 OBJ: 4
TOP:Nursing Process Step: Assessment
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT:CONCEPT(S): Clinical Judgment; Safety
2. The nurse administers an initial dose of a steroid to a patient with asthma.
Thirty minutes after administration, the nurse finds the patient agitated and stating
that “everyone is out to get me.” What is the term for this unusual reaction?
a.Desired action
b.Adverse effect
c.Idiosyncratic reaction
d.Allergic reaction
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is
first administered. Patients typically exhibit an overresponsiveness to a medication
related to diminished metabolism. These reactions are believed to be related to
genetic enzyme deficiencies. Desired actions are expected responses to a
medication. Adverse effects are reactions that occur in another system of the body;
they are usually predictable. Allergic reactions appear after repeated medication
dosages.
DIF: Cognitive Level: Knowledge REF: Page 18 OBJ: 4
TOP:Nursing Process Step: Evaluation
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Patient Education; Clinical Judgment; Caregiving; Safety;
Sensory Perception
3. Which is the best description of when drug interactions occur?
a.On administration of toxic dosages of a drug
, Test Bank for Basic Pharmacology for Nurses 17th Edition
b.On an increase in the pharmacodynamics of bound drugs
c.On the alteration of the effect of one drug by another drug
d.On increase of drug excretion
ANS: C
Drug interactions may be characterized by an increase or decrease in the
effectiveness of one or both of the drugs. Toxicity of one drug may or may not
affect the metabolism of another one. Drug interactions may result from either
increased or decreased pharmacodynamics. Drug interactions may result from
either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: Page 18 OBJ: 5
TOP:Nursing Process Step: Assessment
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT:CONCEPT(S): Safety; Patient Education; Clinical Judgment
4. What occurs when two drugs compete for the same receptor site, resulting
in increased activity of the first drug?
a.Desired action
b.Synergistic effect
c.Carcinogenicity
d.Displacement
ANS: D
The displacement of the first drug from receptor sites by a second drug increases
the amount of the first drug because more unbound drug is available. An expected
response of a drug is the desired action. A synergistic effect is the effect of two
drugs being greater than the effect of each chemical individually or the sum of the
individual effects. Carcinogenicity is the ability of a drug to cause cells to mutate
and become cancerous.
DIF: Cognitive Level: Comprehension REF: Page 19 OBJ: 6
TOP:Nursing Process Step: Implementation
Test Bank for Basic Pharmacology for Nurses 17th Edition by Bruce Clayton and
Michelle Willinganz
Chapter 02: Basic Principles of Drug Action and Drug
Interactions
Clayton/Willihnganz: Basic Pharmacology for Nurses, 17th Edition
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is
the nurse‟s priority action?
a.Notify physician of allergic reaction.
b.Notify physician of idiosyncratic reaction.
c.Notify physician of potential teratogenicity.
d.Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives
and/or urticaria, which are easily identified. An idiosyncratic reaction occurs when
something unusual or abnormal happens when a drug is first administered. A
teratogenic reaction refers to the occurrence of birth defects related to
,Test Bank for Basic Pharmacology for Nurses 17th Edition
administration of the drug. Tolerance refers to the body‟s requirement for
increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: Page 17 OBJ: 4
TOP:Nursing Process Step: Assessment
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT:CONCEPT(S): Clinical Judgment; Safety
2. The nurse administers an initial dose of a steroid to a patient with asthma.
Thirty minutes after administration, the nurse finds the patient agitated and stating
that “everyone is out to get me.” What is the term for this unusual reaction?
a.Desired action
b.Adverse effect
c.Idiosyncratic reaction
d.Allergic reaction
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is
first administered. Patients typically exhibit an overresponsiveness to a medication
related to diminished metabolism. These reactions are believed to be related to
genetic enzyme deficiencies. Desired actions are expected responses to a
medication. Adverse effects are reactions that occur in another system of the body;
they are usually predictable. Allergic reactions appear after repeated medication
dosages.
DIF: Cognitive Level: Knowledge REF: Page 18 OBJ: 4
TOP:Nursing Process Step: Evaluation
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Patient Education; Clinical Judgment; Caregiving; Safety;
Sensory Perception
3. Which is the best description of when drug interactions occur?
a.On administration of toxic dosages of a drug
, Test Bank for Basic Pharmacology for Nurses 17th Edition
b.On an increase in the pharmacodynamics of bound drugs
c.On the alteration of the effect of one drug by another drug
d.On increase of drug excretion
ANS: C
Drug interactions may be characterized by an increase or decrease in the
effectiveness of one or both of the drugs. Toxicity of one drug may or may not
affect the metabolism of another one. Drug interactions may result from either
increased or decreased pharmacodynamics. Drug interactions may result from
either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: Page 18 OBJ: 5
TOP:Nursing Process Step: Assessment
MSC:NCLEX Client Needs Category: Physiological Integrity
NOT:CONCEPT(S): Safety; Patient Education; Clinical Judgment
4. What occurs when two drugs compete for the same receptor site, resulting
in increased activity of the first drug?
a.Desired action
b.Synergistic effect
c.Carcinogenicity
d.Displacement
ANS: D
The displacement of the first drug from receptor sites by a second drug increases
the amount of the first drug because more unbound drug is available. An expected
response of a drug is the desired action. A synergistic effect is the effect of two
drugs being greater than the effect of each chemical individually or the sum of the
individual effects. Carcinogenicity is the ability of a drug to cause cells to mutate
and become cancerous.
DIF: Cognitive Level: Comprehension REF: Page 19 OBJ: 6
TOP:Nursing Process Step: Implementation
