PEPTIC ULCER
DISEASE BY MARY LEDOUX
CHAMBERLAIN UNIVERSITY
NR 565 ADVANCED PHARMACOLOGY FUNDAMENTALS
DR. ELAM
, Stephen is a 38 y.o. patient who is coming into the office for
complaints of upper abdominal pain for a month that usually
occurs 2-3 hours after every meal. He endorses his s/s also
include some nausea, bloating, and occasionally heartburn.
CASE-STUDY He reports a past medical history of migraine headaches in
which he reports he has been taking 800 mg of Motrin to
manage it. He also reports he smokes about 1/2 pack of
cigarettes a day, drinks 3-4 beers before bedtime, and has
been dealing with a lot of stress at his work which has been
triggering his migraines more frequently. He has no known
allergies. His vitals are temp 97.0 F, HR 105, BP 134/76, 20
respirations, and 99% on room air. His lab results which
included a CBC, CMP, and Lipase all were unremarkable. Fecal
occult blood was negative. Your objective findings include
tenderness over the epigastric area and mild tachycardia
based on his vital signs.
, • Peptic ulcers are open sores that develop on the
inside lining of the stomach (gastric) or the
WHAT IS PEPTIC upper portion of the small intestine (duodenum)
(Mayo Clinic, 2020).
ULCER • Peptic ulcers occur because of an imbalance
DISEASE? between aggressive factors (gastric acid and
pepsin) and mechanisms that maintain mucosal
integrity (mucosal defense and repair) (Kumar &
Ashwlayan, 2019).
• Causes: Most common are NSAIDS and H.
pylori bacteria
• Other causes: Steroids, ASA
• Risk Factors: Smoking, Alcohol, Stress
(Mayo Clin
DISEASE BY MARY LEDOUX
CHAMBERLAIN UNIVERSITY
NR 565 ADVANCED PHARMACOLOGY FUNDAMENTALS
DR. ELAM
, Stephen is a 38 y.o. patient who is coming into the office for
complaints of upper abdominal pain for a month that usually
occurs 2-3 hours after every meal. He endorses his s/s also
include some nausea, bloating, and occasionally heartburn.
CASE-STUDY He reports a past medical history of migraine headaches in
which he reports he has been taking 800 mg of Motrin to
manage it. He also reports he smokes about 1/2 pack of
cigarettes a day, drinks 3-4 beers before bedtime, and has
been dealing with a lot of stress at his work which has been
triggering his migraines more frequently. He has no known
allergies. His vitals are temp 97.0 F, HR 105, BP 134/76, 20
respirations, and 99% on room air. His lab results which
included a CBC, CMP, and Lipase all were unremarkable. Fecal
occult blood was negative. Your objective findings include
tenderness over the epigastric area and mild tachycardia
based on his vital signs.
, • Peptic ulcers are open sores that develop on the
inside lining of the stomach (gastric) or the
WHAT IS PEPTIC upper portion of the small intestine (duodenum)
(Mayo Clinic, 2020).
ULCER • Peptic ulcers occur because of an imbalance
DISEASE? between aggressive factors (gastric acid and
pepsin) and mechanisms that maintain mucosal
integrity (mucosal defense and repair) (Kumar &
Ashwlayan, 2019).
• Causes: Most common are NSAIDS and H.
pylori bacteria
• Other causes: Steroids, ASA
• Risk Factors: Smoking, Alcohol, Stress
(Mayo Clin
