module 5
Migraines – what foods might be a trigger? Migraine and seizure get Arul too. Take beta blocker
daily.
- Foods with yeast - Nuts
- MSG - Artificial sweeteners
- Nitrates (meats), - Smoked fish
marinated foods
- Pickled / fermented foods
✓ Chocolate, Cheese, yogurt ,Caffeine, nicotine, ice cream, alcohol, stress, fatigue
✓ Lunch/cured meat, hot dogs, smoked meats, Vinegar, Onions
✓ Caffeine, nicotine, ice cream, alcohol, stress, fatigue
Mechanism of action for ergotamine? Use
for migraine Contraindicated with
coronary
- Ergotamine selectively binds and activates serotonin (5-HT) 1D receptors located on
intracranial blood vessels, including those on arterio-venous anastomoses, thereby resulting
in vasoconstriction and reducing the blood flow in cerebral arteries that may lead to
relieve of vascular headaches.
- Ergotamine has a complex mechanism of action that involves a variety of receptors, including
5-HT-1B/1D, dopamine, and alpha-adrenoreceptors. By activating 5HT-1B and 5HT-1D
receptors on intracranial blood vessels, ergotamine induces vasoconstriction and relief of
migraine headaches.
- Ergotamine also inhibits norepinephrine uptake and stimulates alpha-adrenergic receptors at
therapeutic doses, leading to prolonged vasoconstriction.
S/S of Parkinson’s? Guillain-Barre? With GB what are they most at risk for?? What will kill
them first?
Parkinso Guillain – Barre paralysis(distal to
n’s proximal)
https://www.coursehero.com/file/102594500/mdc4EXAM-1-STUDY-GUIDEdocx/
, Falls (require sx carry risk infection,
- - Motor Manifestations: exposure to
Heart failure and blood clots and zika virus
immobility and PNA, - Risk for infection with
- Tremors (upper extremities first, campylobacter (bacteria un-cook
worsen with stress)^ fatigue, slow poultry) Influenzas virus.
movement cytomegalovirus
• Ascending symmetric muscle
- Change in handwriting
- “Freezing” / stuck to floor
weakness
- Rigidity(rigor). Loss of • /ascendingFlaccid paralysis
movement(Akinesia) without atrophy
- Resistance to PROM • Decreased / absent DTRs
Cogwheel • Respiratory compromise
- Rhythmic interruption of movement suction HOB 45 degree.
Plastic Paralysis of the muscle of lung,
- Mildly restrictive movement
Lead pipe blood infection, clot in lungs, or
- Total resistance to movement cardiac arrest
- Masklike face with wide open, fixed eyes • B&B incontinence
- Uncontrollable drooling • Ataxia
- Excessive perspiration
- Orthostatic hypotension - Sensory Manifestations:
- Speech changes: Bradykinesia – • Parasthesias
slowness of voluntary movement • Pain (cramping)
Cranial nerve Manifestations:
and speech • Facial weakness
• Speak softly. Med only treat the • Dysphagia
symptoms • Diplopia
• Slur / repeat words • Difficulty speaking
• Monotone voice
• Halting speech
- B&B incontinence - Autonomic Manifestations:
• Labile BP
- postural instability.
• Cardiac dysrhythmias / tachycardia
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What condition closely resembles a stroke but isn’t? migraine, seizure, Hypoglycemia, Bell Palsy
https://www.coursehero.com/file/102594500/mdc4EXAM-1-STUDY-GUIDEdocx/