NR 508 Week 4 Midterm Possible Questions and well
explained answers
1. Which of the following has been shown to prolong life in patients with chronic congestive failure in spite
of having a negative inotropic effect on cardiac contractility?
2. Which of the following statements gives the best explanation for the use beta-blockers in congestive
heart failure?
3. Which of the molecular mechanism of action of digoxin (Lanoxin, Cardoxin) used in the management of
congestive heart failure?
4. Which of the following is an aldosterone antagonist and is useful in the management of hypertensive
patients with hypokalemia?
5. Which of the following agents is the most appropriate choice as a diuretic in patients with hypertension,
heart failure and renal failure?
6. Which is the atypical antidepressant known to block the reuptake of dopamine & norepinephrine (NDRI) and
in known to treat depression & nicotine addiction?
7. Which is the drug increase GABA activity & chloride conductance in neuronal cells thus inhibiting
action potentials and is known to treat anxiety, convulsions and could cause marked sedation?
8. Which of the following agents is a carbonic anhydrase inhibitor that works at the proximal convoluted tubule
and is used in the treatment of ocular hypertension?
9. Which class of drugs bind to 30s ribosome units and is used in the treatment of Proponibacterum (
acne), mycoplasma, chlamydae, and helicobacter infections?
10. The primary care NP see a patient several months after a myocardial infarction. The patient has been
furosemide to treat heart failure.. The NP notes that the patient has edema of the hands , feet and ankles. The
NP should add which drug?
11. MK is a 64-year-old male taking Lisinopril for HTN. One month after starting the drug he noted to have a
decline in renal function. Which is true?
12. A 55-year-old patient develops Parkinson's disease characterized by unilateral tumors only. The primary care
NP will referrer the patient to a neurologist and should expect initial treatment to be ?
13. Which of the following drugs is a calcium channel blocker that slows cardiac conduction directly and
thus decreases heart rates and oxygen demand?
14. Which of the following is an approved pharmacologic agent indicated for rapid conversion of atrial
arrhythmias? Prior to the approval, electrical cardioversion was the recommended choice for rapid conversion of
atrial fibrillation to normal sinus rhythm?
15. Early stage Alzheimer's disease is diagnosed in a patient and the primary care NP recommended therapy
is necessary because most functioning is intact. The NP should explain that medication may?
16. LO a 38-year-old with a history of depression and migraine headaches. In mid July she calls your office
worried because she takes fluoxetine and occasionally Sumatriptan and heard a warning was issued re : the use
of the two together. What is the concern?
17. Which of the following agents is most appropriate chose as a diuretic in patients with hypertension,
heart failure and renal failure? ( therapeutic multiple uses )?
18. Which is the antifungal drugs, useful treating fungal meningitis in AIDS patients that reduces
" ergosterol synthesis" in fungal cell membranes by inhibiting 14 alpha demethylases, a fungal cytochome P450
enzyme?
1
, 19. A patient taking hydrochlorothiazide to treat hypertension and ask the primary care NP why it is necessary to
reduce sodium intake while taking this medication. The NP should explain that decreasing sodium is necessary to
?
2
explained answers
1. Which of the following has been shown to prolong life in patients with chronic congestive failure in spite
of having a negative inotropic effect on cardiac contractility?
2. Which of the following statements gives the best explanation for the use beta-blockers in congestive
heart failure?
3. Which of the molecular mechanism of action of digoxin (Lanoxin, Cardoxin) used in the management of
congestive heart failure?
4. Which of the following is an aldosterone antagonist and is useful in the management of hypertensive
patients with hypokalemia?
5. Which of the following agents is the most appropriate choice as a diuretic in patients with hypertension,
heart failure and renal failure?
6. Which is the atypical antidepressant known to block the reuptake of dopamine & norepinephrine (NDRI) and
in known to treat depression & nicotine addiction?
7. Which is the drug increase GABA activity & chloride conductance in neuronal cells thus inhibiting
action potentials and is known to treat anxiety, convulsions and could cause marked sedation?
8. Which of the following agents is a carbonic anhydrase inhibitor that works at the proximal convoluted tubule
and is used in the treatment of ocular hypertension?
9. Which class of drugs bind to 30s ribosome units and is used in the treatment of Proponibacterum (
acne), mycoplasma, chlamydae, and helicobacter infections?
10. The primary care NP see a patient several months after a myocardial infarction. The patient has been
furosemide to treat heart failure.. The NP notes that the patient has edema of the hands , feet and ankles. The
NP should add which drug?
11. MK is a 64-year-old male taking Lisinopril for HTN. One month after starting the drug he noted to have a
decline in renal function. Which is true?
12. A 55-year-old patient develops Parkinson's disease characterized by unilateral tumors only. The primary care
NP will referrer the patient to a neurologist and should expect initial treatment to be ?
13. Which of the following drugs is a calcium channel blocker that slows cardiac conduction directly and
thus decreases heart rates and oxygen demand?
14. Which of the following is an approved pharmacologic agent indicated for rapid conversion of atrial
arrhythmias? Prior to the approval, electrical cardioversion was the recommended choice for rapid conversion of
atrial fibrillation to normal sinus rhythm?
15. Early stage Alzheimer's disease is diagnosed in a patient and the primary care NP recommended therapy
is necessary because most functioning is intact. The NP should explain that medication may?
16. LO a 38-year-old with a history of depression and migraine headaches. In mid July she calls your office
worried because she takes fluoxetine and occasionally Sumatriptan and heard a warning was issued re : the use
of the two together. What is the concern?
17. Which of the following agents is most appropriate chose as a diuretic in patients with hypertension,
heart failure and renal failure? ( therapeutic multiple uses )?
18. Which is the antifungal drugs, useful treating fungal meningitis in AIDS patients that reduces
" ergosterol synthesis" in fungal cell membranes by inhibiting 14 alpha demethylases, a fungal cytochome P450
enzyme?
1
, 19. A patient taking hydrochlorothiazide to treat hypertension and ask the primary care NP why it is necessary to
reduce sodium intake while taking this medication. The NP should explain that decreasing sodium is necessary to
?
2
