Diagnosis: Urolithiasis
Signs and Symptoms Physical Assessment Findings
Pathophysiology Summary Pharmacologic Recommendations
(subjective) (objective)
Ibuprofen – non-steroidal anti-
Fever
inflammatory drug; Dosing –
The development of calculi Urinalysis – may
600mg by mouth every 8 hours for
anywhere within the urinary tract. indicate presence of
7-14 days. MOA – exact mechanism
Stones may be small or large. Calculi bacteria, or blood in
of action unknown; inhibits
form due to excessive amounts of urine
cyclooxygenase, reducing
insoluble salts in the filtrate or when Flank pain CBC – may be elevated
prostaglandin and thromboxane
insufficient fluid intake creates highly Nausea in presence of infection
synthesis[ CITATION epo201 \l
concentrated filtrate. Cell debris from Feeling clammy X-ray – may indicate
1033 ]
infection may develop into a stone. Painful urination hydronephrosis, if
Acetaminophen – analgesic pain
Immobility can result in calculi Frequent urination present, and location of
medication; Dosing – 325-1000mg
formation due to stasis of urine. Abnormally colored stones[ CITATION
every 4-6 hours as needed, max
Stones generally cause manifestations urine[ CITATION May192 \l 1033 ]
dose 4g/day. MOA – analgesic
only when obstruction is present. May192 \l 1033 ] Ascorbic acid –
mechanism of action unknown;
Calculi formation may cause the increased values may
antipyretic effect via direct action
development of hydronephrosis increase stone
on the hypothalamic heat regulating
(Hubert & VanMeter, 2018). formation[ CITATION
center [ CITATION epo20 \l 1033 ]
Jia19 \l 1033 ].
Signs and Symptoms Physical Assessment Findings
Pathophysiology Summary Pharmacologic Recommendations
(subjective) (objective)
Ibuprofen – non-steroidal anti-
Fever
inflammatory drug; Dosing –
The development of calculi Urinalysis – may
600mg by mouth every 8 hours for
anywhere within the urinary tract. indicate presence of
7-14 days. MOA – exact mechanism
Stones may be small or large. Calculi bacteria, or blood in
of action unknown; inhibits
form due to excessive amounts of urine
cyclooxygenase, reducing
insoluble salts in the filtrate or when Flank pain CBC – may be elevated
prostaglandin and thromboxane
insufficient fluid intake creates highly Nausea in presence of infection
synthesis[ CITATION epo201 \l
concentrated filtrate. Cell debris from Feeling clammy X-ray – may indicate
1033 ]
infection may develop into a stone. Painful urination hydronephrosis, if
Acetaminophen – analgesic pain
Immobility can result in calculi Frequent urination present, and location of
medication; Dosing – 325-1000mg
formation due to stasis of urine. Abnormally colored stones[ CITATION
every 4-6 hours as needed, max
Stones generally cause manifestations urine[ CITATION May192 \l 1033 ]
dose 4g/day. MOA – analgesic
only when obstruction is present. May192 \l 1033 ] Ascorbic acid –
mechanism of action unknown;
Calculi formation may cause the increased values may
antipyretic effect via direct action
development of hydronephrosis increase stone
on the hypothalamic heat regulating
(Hubert & VanMeter, 2018). formation[ CITATION
center [ CITATION epo20 \l 1033 ]
Jia19 \l 1033 ].
