Stuvia.com - The Marketplace to Buy and Sell your Study Material
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Test Bank
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is the nurse’s priority
action?
a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
which are easily identified. An idiosyncratic reaction occurs when something unusual or
abnormal happens when a drug is first administered. A teratogenic reaction refers to the
occurrence of birth defects related to administration of the drug. Tolerance refers to the body’s
requirement for increasing dosages to achieve the same effects that a lower dose once did.
m
er as
DIF: Cognitive Level: Application REF: p. 17 OBJ: 7
co
TOP: Nursing Process Step: Assessment
eH w
MSC: NCLEX Client Needs Category: Physiological Integrity
o.
rs e
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes after
ou urc
administration, the nurse finds the patient agitated and stating that “everyone is out to get me.”
What is the term for this unusual reaction?
a. Desired action
b. Adverse effect
o
c. Idiosyncratic reaction
aC s
d. Allergic reaction
vi y re
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
administered. Patients typically exhibit an overresponsiveness to a medication related to
ed d
diminished metabolism. These reactions are believed to be related to genetic enzyme
ar stu
deficiencies. Desired actions are expected responses to a medication. Adverse effects are
reactions that occur in another system of the body; they are usually predictable. Allergic
reactions appear after repeated medication dosages.
is
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 7
Th
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. Which is the best description of when drug interactions occur?
sh
a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
c. On the alteration of the effect of one drug by another drug
d. On increase of drug excretion
ANS: C
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:26:44 GMT -05:00
https://www.coursehero.com/file/8889649/CH-2-Basic-Principles-of-Drug-Action-and-Drug-Interactions/
Downloaded by: Sophiie |
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
Drug interactions may be characterized by an increase or decrease in the effectiveness of one
or both of the drugs. Toxicity of one drug may or may not affect the metabolism of another
one. Drug interactions may result from either increased or decreased pharmacodynamics.
Drug interactions may result from either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 8
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. What occurs when two drugs compete for the same receptor site, resulting in increased
activity of the first drug?
a. Desired action
b. Synergistic effect
c. Carcinogenicity
d. Displacement
ANS: D
The displacement of the first drug from receptor sites by a second drug increases the amount
of the first drug because more unbound drug is available. An expected response of a drug is
m
the desired action. A synergistic effect is the effect of two drugs being greater than the effect
er as
of each chemical individually, or the sum of the individual effects. Carcinogenicity is the
co
ability of a drug to cause cells to mutate and become cancerous.
eH w
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 9
o.
rs e
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
ou urc
5. What do drug blood levels indicate?
a. They confirm if the patient is taking a generic form of a drug.
o
b. They determine if the patient has sufficient body fat to metabolize the drug.
aC s
c. They verify if the patient is taking someone else’s medications.
vi y re
d. They determine if the amount of drug in the body is in a therapeutic range.
ANS: D
The amount of drug present may vary over time and the blood level must remain in a
ed d
therapeutic range in order to obtain the desired result. Generic drugs do not necessarily
ar stu
produce a different drug blood level than proprietary medications. Body fat is not measured
by drug blood levels. Drug blood levels only measure the amount of drug in the body; they do
not determine the source of the medication.
is
DIF: Cognitive Level: Comprehension REF: p. 16 OBJ: 7
TOP: Nursing Process Step: Evaluation
Th
MSC: NCLEX Client Needs Category: Physiological Integrity
6. What is the process by which a drug is transported by circulating body fluids to receptor sites?
sh
a. Osmosis
b. Distribution
c. Absorption
d. Biotransformation
ANS: B
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:26:44 GMT -05:00
https://www.coursehero.com/file/8889649/CH-2-Basic-Principles-of-Drug-Action-and-Drug-Interactions/
Downloaded by: Sophiie |
Distribution of this document is illegal
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Test Bank
MULTIPLE CHOICE
1. The nurse assesses hives in a patient started on a new medication. What is the nurse’s priority
action?
a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
which are easily identified. An idiosyncratic reaction occurs when something unusual or
abnormal happens when a drug is first administered. A teratogenic reaction refers to the
occurrence of birth defects related to administration of the drug. Tolerance refers to the body’s
requirement for increasing dosages to achieve the same effects that a lower dose once did.
m
er as
DIF: Cognitive Level: Application REF: p. 17 OBJ: 7
co
TOP: Nursing Process Step: Assessment
eH w
MSC: NCLEX Client Needs Category: Physiological Integrity
o.
rs e
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes after
ou urc
administration, the nurse finds the patient agitated and stating that “everyone is out to get me.”
What is the term for this unusual reaction?
a. Desired action
b. Adverse effect
o
c. Idiosyncratic reaction
aC s
d. Allergic reaction
vi y re
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
administered. Patients typically exhibit an overresponsiveness to a medication related to
ed d
diminished metabolism. These reactions are believed to be related to genetic enzyme
ar stu
deficiencies. Desired actions are expected responses to a medication. Adverse effects are
reactions that occur in another system of the body; they are usually predictable. Allergic
reactions appear after repeated medication dosages.
is
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 7
Th
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. Which is the best description of when drug interactions occur?
sh
a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
c. On the alteration of the effect of one drug by another drug
d. On increase of drug excretion
ANS: C
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:26:44 GMT -05:00
https://www.coursehero.com/file/8889649/CH-2-Basic-Principles-of-Drug-Action-and-Drug-Interactions/
Downloaded by: Sophiie |
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
Drug interactions may be characterized by an increase or decrease in the effectiveness of one
or both of the drugs. Toxicity of one drug may or may not affect the metabolism of another
one. Drug interactions may result from either increased or decreased pharmacodynamics.
Drug interactions may result from either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 8
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. What occurs when two drugs compete for the same receptor site, resulting in increased
activity of the first drug?
a. Desired action
b. Synergistic effect
c. Carcinogenicity
d. Displacement
ANS: D
The displacement of the first drug from receptor sites by a second drug increases the amount
of the first drug because more unbound drug is available. An expected response of a drug is
m
the desired action. A synergistic effect is the effect of two drugs being greater than the effect
er as
of each chemical individually, or the sum of the individual effects. Carcinogenicity is the
co
ability of a drug to cause cells to mutate and become cancerous.
eH w
DIF: Cognitive Level: Comprehension REF: p. 17 OBJ: 9
o.
rs e
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
ou urc
5. What do drug blood levels indicate?
a. They confirm if the patient is taking a generic form of a drug.
o
b. They determine if the patient has sufficient body fat to metabolize the drug.
aC s
c. They verify if the patient is taking someone else’s medications.
vi y re
d. They determine if the amount of drug in the body is in a therapeutic range.
ANS: D
The amount of drug present may vary over time and the blood level must remain in a
ed d
therapeutic range in order to obtain the desired result. Generic drugs do not necessarily
ar stu
produce a different drug blood level than proprietary medications. Body fat is not measured
by drug blood levels. Drug blood levels only measure the amount of drug in the body; they do
not determine the source of the medication.
is
DIF: Cognitive Level: Comprehension REF: p. 16 OBJ: 7
TOP: Nursing Process Step: Evaluation
Th
MSC: NCLEX Client Needs Category: Physiological Integrity
6. What is the process by which a drug is transported by circulating body fluids to receptor sites?
sh
a. Osmosis
b. Distribution
c. Absorption
d. Biotransformation
ANS: B
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:26:44 GMT -05:00
https://www.coursehero.com/file/8889649/CH-2-Basic-Principles-of-Drug-Action-and-Drug-Interactions/
Downloaded by: Sophiie |
Distribution of this document is illegal
