Onset, Action gna Interactions Responsibilities
Duration of ncy
Action
Thyroid Levoyhtroxine PO, IV Identical to Primary and Hypersensitivity Rare at A Can Elderly pts
Hormone (Synthroid, (myxedem thyroid secondary Thyrotoxicosis therapeutic interact go low and go
Replacement Levothyroid, a coma) hormone: hypothyroidism, Severe CV doses with slow
Synthetic T4 etc.) PO: slow increasing or hypothyroid conditions, MI At high doses: grapefruit Measure TSH
oLiothyronine onset metabolic state resulting Adrenal o CV juice serum levels
(cytomel) IV: 6-8 hrs rate from surgical insufficiency (tachycardia, delay to see
oLiotrix DOA: 1-3 (increasing O2 removal of angina) absorption progression
(thyrolar) weeks, consumption, thyroid gland, o CNS of therapy
oThyroid, half life 6- resps, and radiation, or excitability Amount of
desiccated 7 days HR) congenital (tremors, absorption
(armour) Increase rate defect headache, and
of nervousness, bioavailability
metabolism insomnia) varies by
promotes o ↑ metabolism brand stick
growth and can create to 1 brand,
maturation strain on heart don’t switch
by making Lifelong;
body work initially –
harder evaluate
every 2 weeks
Taken
separate from
other meds
for absorption
Taken in
morning
before
breakfast
Check BP, HR,
temp
IF HR > 100
DO NOT GIVE
CNS
excitabilities
check
alertness
, Classification Prototype Routes, Mechanisms Indications Contraindications Adverse Effects Preg Drug Nursing
Onset, of Action nanc Inter Responsibiliti
Duration y actio es
of Action ns
Thyroid Propylthiouracil PO Inhibits the Hyperthyroidism Hypersensitivity Leukopenia 0 blood dyscrasias D Overdose
Hormone (PTU) Onset: first step in Give prior to Caution: bone Glomerulonephritis give
Inhibitor oLugol’s solution weeks thyroid surgery if marrow Arthralgias and joint swelling Synthroid
oMethimazole DOA: hormone someone will depression, liver CNS – HA, vertigo, paresthesias
(Tapazole) 1-1.5 synthesis, have part of disease Goiter at high doses
oPotassium hrs suppresses thyroid removed
Iodide (Thyro- peripheral
Block) conversion
oRadioactive of T4 to T3
iodine