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Chapter 21: Drugs Used to Treat Dyslipidemias
Test Bank
MULTIPLE CHOICE
1. Which lipoprotein contributes to the development of atherosclerosis?
a. Chylomicrons
b. Very-low-density lipoprotein (VLDL)
c. Low-density lipoprotein chylomicron (LDL C)
d. High-density lipoprotein chylomicron (HDL C)
ANS: C
The probability that atherosclerosis will develop is related directly to the concentration of
LDL C. Chylomicrons are intermediate-density lipoproteins. VLDLs are not as important in
the development of atherosclerosis as low-density lipoproteins. HDLs do not contribute to the
development of atherosclerosis.
DIF: Cognitive Level: Comprehension REF: p. 344 OBJ: 2
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
2. The nurse is preparing medications for a patient. When is the best time for the nurse to
administer lovastatin (Mevacor)?
a. 2 hours after breakfast
b. During the patient’s dinner
c. 1 hour before breakfast
d. 30 minutesbefore lunch
ANS: B
Lovastatin should be administered with food to enhance absorption, and in the evening,
because this is when the production of cholesterol is at its highest. It is not recommended that
lovastatin be taken after food but while eating to enhance absorption. Taking the medication a
half hour or an hour before eating would not benefit the patient or enhance absorption.
DIF: Cognitive Level: Application REF: pp. 350-351 OBJ: 5
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. The nurse has completed an admitting patient history and notes the patient’s current
medications to be simvastatin (Zocor) and warfarin (Coumadin). What is the result of the
interaction of these drugs?
a. Abdominal distention
b. Increased INR
c. Low serum level of simvastatin
d. Hypertension
ANS: B
The combined therapy of simvastatin and warfarin may prolong the patient’s INR. Additional
nursing assessments would include monitoring for possible overcoagulation and bleeding.
Abdominal distention and a low serum level of simvastatin does not occur with the combined
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therapy of simvastatin and warfarin. Increased blood pressure is not a complication of
combining simvastatin and warfarin therapy.
DIF: Cognitive Level: ComprehensionREF: p. 353 OBJ: 5
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
4. Which deficiency may develop in patients taking cholestyramine?
a. Potassium deficiency
b. Sodium deficiency
c. Vitamin K deficiency
d. Hydrochloric acid deficiency
ANS: C
Patients on long term bile acid–sequestering resin therapy may become deficient in fat
soluble vitamins (i.e., D, E, A, K). Cholestyramine does not affect electrolyte levels or
hydrochloric acid.
DIF: Cognitive Level: Knowledge REF: p. 348 OBJ: 4
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
5. A patient is prescribed a bile acid resin. The nurse instructs the patient to report which
adverse reaction related to vitamin K deficiency?
a. Constipation
b. Coffee ground emesis
c. Nausea
d. Changes in skin pigmentation
ANS: B
Vitamin K is essential for blood clotting. Signs and symptoms of a vitamin K deficiency include
bleeding gums, bruising, dark tarry stools, and coffee ground emesis (blood vomited from the
stomach). Constipation, nausea, and a change in skin pigmentation are not signs of vitamin K
deficiency.
DIF: Cognitive Level: Application REF: p. 347 OBJ: 5
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Health Promotion and Maintenance
6. Which vitamin has antilipemic actions?
a. C
b. A
c. D
d. B3
ANS: D
It is thought that niacin inhibits VLDL synthesis by liver cells, causing a decrease in LDL and
triglyceride production. Vitamins A, C, and D do not have an antilipemic effects.
DIF: Cognitive Level: Knowledge REF: p. 349 OBJ: 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Health Promotion and Maintenance
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Chapter 21: Drugs Used to Treat Dyslipidemias
Test Bank
MULTIPLE CHOICE
1. Which lipoprotein contributes to the development of atherosclerosis?
a. Chylomicrons
b. Very-low-density lipoprotein (VLDL)
c. Low-density lipoprotein chylomicron (LDL C)
d. High-density lipoprotein chylomicron (HDL C)
ANS: C
The probability that atherosclerosis will develop is related directly to the concentration of
LDL C. Chylomicrons are intermediate-density lipoproteins. VLDLs are not as important in
the development of atherosclerosis as low-density lipoproteins. HDLs do not contribute to the
development of atherosclerosis.
DIF: Cognitive Level: Comprehension REF: p. 344 OBJ: 2
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
2. The nurse is preparing medications for a patient. When is the best time for the nurse to
administer lovastatin (Mevacor)?
a. 2 hours after breakfast
b. During the patient’s dinner
c. 1 hour before breakfast
d. 30 minutesbefore lunch
ANS: B
Lovastatin should be administered with food to enhance absorption, and in the evening,
because this is when the production of cholesterol is at its highest. It is not recommended that
lovastatin be taken after food but while eating to enhance absorption. Taking the medication a
half hour or an hour before eating would not benefit the patient or enhance absorption.
DIF: Cognitive Level: Application REF: pp. 350-351 OBJ: 5
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. The nurse has completed an admitting patient history and notes the patient’s current
medications to be simvastatin (Zocor) and warfarin (Coumadin). What is the result of the
interaction of these drugs?
a. Abdominal distention
b. Increased INR
c. Low serum level of simvastatin
d. Hypertension
ANS: B
The combined therapy of simvastatin and warfarin may prolong the patient’s INR. Additional
nursing assessments would include monitoring for possible overcoagulation and bleeding.
Abdominal distention and a low serum level of simvastatin does not occur with the combined
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:39:37 GMT -05:00
https://www.coursehero.com/file/19255149/ch22/
Downloaded by: Sophiie |
Distribution of this document is illegal
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therapy of simvastatin and warfarin. Increased blood pressure is not a complication of
combining simvastatin and warfarin therapy.
DIF: Cognitive Level: ComprehensionREF: p. 353 OBJ: 5
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
4. Which deficiency may develop in patients taking cholestyramine?
a. Potassium deficiency
b. Sodium deficiency
c. Vitamin K deficiency
d. Hydrochloric acid deficiency
ANS: C
Patients on long term bile acid–sequestering resin therapy may become deficient in fat
soluble vitamins (i.e., D, E, A, K). Cholestyramine does not affect electrolyte levels or
hydrochloric acid.
DIF: Cognitive Level: Knowledge REF: p. 348 OBJ: 4
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
5. A patient is prescribed a bile acid resin. The nurse instructs the patient to report which
adverse reaction related to vitamin K deficiency?
a. Constipation
b. Coffee ground emesis
c. Nausea
d. Changes in skin pigmentation
ANS: B
Vitamin K is essential for blood clotting. Signs and symptoms of a vitamin K deficiency include
bleeding gums, bruising, dark tarry stools, and coffee ground emesis (blood vomited from the
stomach). Constipation, nausea, and a change in skin pigmentation are not signs of vitamin K
deficiency.
DIF: Cognitive Level: Application REF: p. 347 OBJ: 5
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Health Promotion and Maintenance
6. Which vitamin has antilipemic actions?
a. C
b. A
c. D
d. B3
ANS: D
It is thought that niacin inhibits VLDL synthesis by liver cells, causing a decrease in LDL and
triglyceride production. Vitamins A, C, and D do not have an antilipemic effects.
DIF: Cognitive Level: Knowledge REF: p. 349 OBJ: 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Health Promotion and Maintenance
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 14:39:37 GMT -05:00
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