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Chapter 44: Drugs Used to Treat the Musculoskeletal System
MULTIPLE CHOICE
1. A patient who has undergone a lengthy surgical procedure under general anesthesia is
unable to breathe on his own following the procedure. Which drug will the nurse expect to
be administered as an antidote to the neuromuscular-blocking agent?
a. Dantrolene (Dantrium)
b. Neostigmine methylsulfate (Prostigmin)
c. Ether
d. Baclofen (Lioresal)
ANS: B
Neostigmine methylsulfate is an antidote to neuromuscular-blocking agents. Additional
measures to implement include artificial respirations with oxygen and atropine sulfate for
bradycardia and hypotension. Dantrolene is a direct-acting skeletal muscle relaxant given for
the treatment of neuroleptic malignant syndrome associated with the use of antipsychotic
agents. Ether is a general anesthetic. Baclofen is a skeletal muscle relaxant.
DIF: Cognitive Level: Application REF: Page 684 OBJ: 4
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Safety; Gas Exchange
2. What is the reason for a paraplegic patient to receive baclofen (Lioresal)?
a. It interrupts reflexes at the level of the spinal cord.
b. It acts directly on the skeletal muscles to reduce spasticity.
c. It interrupts transmission of impulses from motor nerves to muscles at the skeletal
neuromuscular junction.
d. It produces generalized mild weakness of skeletal muscles and decreases the force of
reflex muscle contractions.
ANS: A
Baclofen is a gamma aminobutyric acid derivative that interrupts polysynaptic reflexes at the
level of the spinal cord. Baclofen does not appear to act directly on the skeletal muscles.
Interrupting transmission of impulses from motor nerves to muscles at the skeletal
neuromuscular junction is the mechanism of action of neuromuscular-blocking agents.
Producing generalized mild weakness of skeletal muscles and decreasing the force of reflex
muscle contractions is the mechanism of action of dantrolene.
DIF: Cognitive Level: ComprehensionREF: Page 682 OBJ: 2 | 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment
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3. A patient taking antipsychotic medication for schizophrenia is admitted with a temperature
of 106° F. The admitting diagnosis is neuroleptic malignant syndrome resulting from
antipsychotic medication. Which drug is indicated in treatment of this condition?
a. Edrophonium (Tensilon)
b. Dantrolene (Dantrium)
c. Baclofen (Lioresal)
d. Metaxalone (Skelaxin)
ANS: B
Dantrolene, a direct-acting skeletal muscle relaxant, is used to treat neuroleptic malignant
syndrome associated with the use of antipsychotic agents. Edrophonium is an antidote for
neuromuscular-blocking agents. Baclofen is a skeletal muscle relaxant used for the treatment
of muscle spasticity resulting from multiple sclerosis (MS) and cerebral palsy. Metaxalone is
used for muscle spasms.
DIF: Cognitive Level: ComprehensionREF: Page 683 OBJ: 2 | 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Safety
4. In the intensive care unit, the nurse is taking care of a patient who is on a ventilator and is
receiving succinylcholine (Anectine). Which is a priority nursing diagnosis for this patient? a.
Pain
b. Disturbed body image
c. Risk for injury
d. Self-care deficit
ANS: A
Pain is the highest priority, according to Maslow’s hierarchy of needs. Succinylcholine, a
neuromuscular-blocking agent, is used to paralyze muscles while a patient is on a ventilator.
Neuromuscular-blocking agents do not relieve pain. Disturbed body image is not a priority for
this situation, although it does apply. Risk for injury and self-care deficit are not as great of
priorities for this situation.
DIF: Cognitive Level: Application REF: Page 684 | Page 685
OBJ: 1 | 4 TOP: Nursing Process Step: Diagnosis
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Pain
5. The patient’s family asks why neuromuscular blocking agents are used before
electroconvulsive therapy. Which explanation by the nurse is most accurate?
a. “They stimulate respirations while therapy is delivered.”
b. “They prevent aspiration of respiratory secretions during the therapy.”
c. “They decrease intracranial pressure resulting from therapy.”
d. “They reduce the risk of injury during therapy.”
ANS: D
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Chapter 44: Drugs Used to Treat the Musculoskeletal System
MULTIPLE CHOICE
1. A patient who has undergone a lengthy surgical procedure under general anesthesia is
unable to breathe on his own following the procedure. Which drug will the nurse expect to
be administered as an antidote to the neuromuscular-blocking agent?
a. Dantrolene (Dantrium)
b. Neostigmine methylsulfate (Prostigmin)
c. Ether
d. Baclofen (Lioresal)
ANS: B
Neostigmine methylsulfate is an antidote to neuromuscular-blocking agents. Additional
measures to implement include artificial respirations with oxygen and atropine sulfate for
bradycardia and hypotension. Dantrolene is a direct-acting skeletal muscle relaxant given for
the treatment of neuroleptic malignant syndrome associated with the use of antipsychotic
agents. Ether is a general anesthetic. Baclofen is a skeletal muscle relaxant.
DIF: Cognitive Level: Application REF: Page 684 OBJ: 4
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Safety; Gas Exchange
2. What is the reason for a paraplegic patient to receive baclofen (Lioresal)?
a. It interrupts reflexes at the level of the spinal cord.
b. It acts directly on the skeletal muscles to reduce spasticity.
c. It interrupts transmission of impulses from motor nerves to muscles at the skeletal
neuromuscular junction.
d. It produces generalized mild weakness of skeletal muscles and decreases the force of
reflex muscle contractions.
ANS: A
Baclofen is a gamma aminobutyric acid derivative that interrupts polysynaptic reflexes at the
level of the spinal cord. Baclofen does not appear to act directly on the skeletal muscles.
Interrupting transmission of impulses from motor nerves to muscles at the skeletal
neuromuscular junction is the mechanism of action of neuromuscular-blocking agents.
Producing generalized mild weakness of skeletal muscles and decreasing the force of reflex
muscle contractions is the mechanism of action of dantrolene.
DIF: Cognitive Level: ComprehensionREF: Page 682 OBJ: 2 | 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment
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Downloaded by: Sophiie |
Distribution of this document is illegal
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3. A patient taking antipsychotic medication for schizophrenia is admitted with a temperature
of 106° F. The admitting diagnosis is neuroleptic malignant syndrome resulting from
antipsychotic medication. Which drug is indicated in treatment of this condition?
a. Edrophonium (Tensilon)
b. Dantrolene (Dantrium)
c. Baclofen (Lioresal)
d. Metaxalone (Skelaxin)
ANS: B
Dantrolene, a direct-acting skeletal muscle relaxant, is used to treat neuroleptic malignant
syndrome associated with the use of antipsychotic agents. Edrophonium is an antidote for
neuromuscular-blocking agents. Baclofen is a skeletal muscle relaxant used for the treatment
of muscle spasticity resulting from multiple sclerosis (MS) and cerebral palsy. Metaxalone is
used for muscle spasms.
DIF: Cognitive Level: ComprehensionREF: Page 683 OBJ: 2 | 3
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Safety
4. In the intensive care unit, the nurse is taking care of a patient who is on a ventilator and is
receiving succinylcholine (Anectine). Which is a priority nursing diagnosis for this patient? a.
Pain
b. Disturbed body image
c. Risk for injury
d. Self-care deficit
ANS: A
Pain is the highest priority, according to Maslow’s hierarchy of needs. Succinylcholine, a
neuromuscular-blocking agent, is used to paralyze muscles while a patient is on a ventilator.
Neuromuscular-blocking agents do not relieve pain. Disturbed body image is not a priority for
this situation, although it does apply. Risk for injury and self-care deficit are not as great of
priorities for this situation.
DIF: Cognitive Level: Application REF: Page 684 | Page 685
OBJ: 1 | 4 TOP: Nursing Process Step: Diagnosis
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Pain
5. The patient’s family asks why neuromuscular blocking agents are used before
electroconvulsive therapy. Which explanation by the nurse is most accurate?
a. “They stimulate respirations while therapy is delivered.”
b. “They prevent aspiration of respiratory secretions during the therapy.”
c. “They decrease intracranial pressure resulting from therapy.”
d. “They reduce the risk of injury during therapy.”
ANS: D
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