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Chapter 38: Gonadal Hormones
Test Bank
MULTIPLE CHOICE
1. A female patient with a history of endometriosis presents with bilateral lower quadrant pain
reportedly at midcycle. Which gonadal drug is indicated for treating symptoms of
endometriosis?
a. Estrogen
b. Progesterone
c. Androgens
d. Gonadotropins
ANS: B
Progesterones are used to treat secondary amenorrhea, breakthrough uterine bleeding, and
endometriosis. They may be combined with estrogens as contraceptives. Estrogen products
are used for relieving the hot flash symptoms of menopause; for contraception; for hormone
replacement therapy after an oophorectomy; in conjunction with appropriate diet, calcium,
and physical therapy in the treatment of osteoporosis; for treatment of severe acne in
females; and to slow the disease progress (and minimize discomfort) in patients with
advanced prostatic cancer and certain types of breast cancer. Androgens are used to treat
hypogonadism, eunuchism, androgen deficiency, and palliation of breast cancer in
postmenopausal women with certain cell types of cancer. When androgens are used for
palliation of cancer in women, they suppress cancer cell growth. Gonadotropin is a hormone
secreted in the pituitary; it regulates the release of the gonadal hormones.
DIF: Cognitive Level: ComprehensionREF: p. 616 OBJ: 3
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
2. What is the rationale for using an androgen as part of breast cancer treatment?
a. For maintenance of fat stores
b. To promote nutrition
c. To prevent wasting resulting from cancer growth
d. For palliative treatment to suppress cancer cell growth
ANS: D
When androgens are used for palliation of breast cancer in women, they suppress cancer cell
growth. Androgens affect muscle growth, not fat stores. Estrogen affects fat stores. Although
androgens may be used to stimulate appetite and improve nutrition, this is not the indication
in this case. Although androgens may be used to prevent wasting, this is not the indication in
this case.
DIF: Cognitive Level: ComprehensionREF: p. 617 OBJ: 2 | 4
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. The health of a patient receiving androgen therapy for breast cancer declines and she
becomes bed bound. Which condition will this patient be at risk of developing?
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a. Electrolyte imbalances
b. Hypercalcemia
c. Hyperglycemia
d. Fluid overload
ANS: B
Immobilized patients receiving androgens for palliative breast cancer treatment are at risk for
hypercalcemia. The nurse should monitor patients for nausea, vomiting, constipation, poor
muscle tone, and lethargy. Immobilization does not affect electrolyte balance, blood glucose,
or fluid balance in this case.
DIF: Cognitive Level: ComprehensionREF: p. 617 OBJ: 2
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. Which patient on oral contraceptive therapy will be at greatest risk for heart attack?
a. A 34-year-old woman with a history of osteoporosis
b. A 28-year-old woman with a history of eczema
c. A 36-year-old woman who smokes half a pack per day
d. A 36-year-old woman who has a history of abnormal Pap smears
ANS: C
The incidence of fatal heart attacks is increased for women older than 35 years of age who
use gonadal hormones and smoke. Osteoporosis, eczema, and cervical dysplasia do not
increase risk for heart attack.
DIF: Cognitive Level: Application REF: p. 613 OBJ: 4
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
5. Which is most important for the nurse to remember when instructing the patient about
treatment with gonadal hormones?
a. Dosage, schedule, and adverse effects
b. Cost, storage, and route of administration
c. Drug interactions and food interactions
d. Scheduling follow up appointments and lab studies
ANS: A
Most gonadal hormones are prescribed to patients for prolonged self administration.
Therefore, planning should stress patient education specific to the type of gonadal hormone
prescribed and its intended actions, including monitoring of adverse effects to expect and
report. Cost, storage, and route of administration are lesser concerns. There are few, if any,
interactions between gonadal hormones and food or other drugs. Follow up appointments
and lab studies are lesser concerns.
DIF: Cognitive Level: Application REF: p. 613 OBJ: 2 |4| 5
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity
6. The nurse is teaching a young woman about birth control pills. For which situation will the
patient need to seek immediate follow up with the health care provider?
a. Breakthrough bleeding
b. Nausea
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Chapter 38: Gonadal Hormones
Test Bank
MULTIPLE CHOICE
1. A female patient with a history of endometriosis presents with bilateral lower quadrant pain
reportedly at midcycle. Which gonadal drug is indicated for treating symptoms of
endometriosis?
a. Estrogen
b. Progesterone
c. Androgens
d. Gonadotropins
ANS: B
Progesterones are used to treat secondary amenorrhea, breakthrough uterine bleeding, and
endometriosis. They may be combined with estrogens as contraceptives. Estrogen products
are used for relieving the hot flash symptoms of menopause; for contraception; for hormone
replacement therapy after an oophorectomy; in conjunction with appropriate diet, calcium,
and physical therapy in the treatment of osteoporosis; for treatment of severe acne in
females; and to slow the disease progress (and minimize discomfort) in patients with
advanced prostatic cancer and certain types of breast cancer. Androgens are used to treat
hypogonadism, eunuchism, androgen deficiency, and palliation of breast cancer in
postmenopausal women with certain cell types of cancer. When androgens are used for
palliation of cancer in women, they suppress cancer cell growth. Gonadotropin is a hormone
secreted in the pituitary; it regulates the release of the gonadal hormones.
DIF: Cognitive Level: ComprehensionREF: p. 616 OBJ: 3
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
2. What is the rationale for using an androgen as part of breast cancer treatment?
a. For maintenance of fat stores
b. To promote nutrition
c. To prevent wasting resulting from cancer growth
d. For palliative treatment to suppress cancer cell growth
ANS: D
When androgens are used for palliation of breast cancer in women, they suppress cancer cell
growth. Androgens affect muscle growth, not fat stores. Estrogen affects fat stores. Although
androgens may be used to stimulate appetite and improve nutrition, this is not the indication
in this case. Although androgens may be used to prevent wasting, this is not the indication in
this case.
DIF: Cognitive Level: ComprehensionREF: p. 617 OBJ: 2 | 4
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
3. The health of a patient receiving androgen therapy for breast cancer declines and she
becomes bed bound. Which condition will this patient be at risk of developing?
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a. Electrolyte imbalances
b. Hypercalcemia
c. Hyperglycemia
d. Fluid overload
ANS: B
Immobilized patients receiving androgens for palliative breast cancer treatment are at risk for
hypercalcemia. The nurse should monitor patients for nausea, vomiting, constipation, poor
muscle tone, and lethargy. Immobilization does not affect electrolyte balance, blood glucose,
or fluid balance in this case.
DIF: Cognitive Level: ComprehensionREF: p. 617 OBJ: 2
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
4. Which patient on oral contraceptive therapy will be at greatest risk for heart attack?
a. A 34-year-old woman with a history of osteoporosis
b. A 28-year-old woman with a history of eczema
c. A 36-year-old woman who smokes half a pack per day
d. A 36-year-old woman who has a history of abnormal Pap smears
ANS: C
The incidence of fatal heart attacks is increased for women older than 35 years of age who
use gonadal hormones and smoke. Osteoporosis, eczema, and cervical dysplasia do not
increase risk for heart attack.
DIF: Cognitive Level: Application REF: p. 613 OBJ: 4
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
5. Which is most important for the nurse to remember when instructing the patient about
treatment with gonadal hormones?
a. Dosage, schedule, and adverse effects
b. Cost, storage, and route of administration
c. Drug interactions and food interactions
d. Scheduling follow up appointments and lab studies
ANS: A
Most gonadal hormones are prescribed to patients for prolonged self administration.
Therefore, planning should stress patient education specific to the type of gonadal hormone
prescribed and its intended actions, including monitoring of adverse effects to expect and
report. Cost, storage, and route of administration are lesser concerns. There are few, if any,
interactions between gonadal hormones and food or other drugs. Follow up appointments
and lab studies are lesser concerns.
DIF: Cognitive Level: Application REF: p. 613 OBJ: 2 |4| 5
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity
6. The nurse is teaching a young woman about birth control pills. For which situation will the
patient need to seek immediate follow up with the health care provider?
a. Breakthrough bleeding
b. Nausea
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