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TEAS-science-anatomy-and-physiology-guide 2022

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Integumentary System Epidermis: Most superficial layer of skin; entirely epithelial cells ● Does NOT contain blood vessels ● 5 layers o Stratum Corneum: "Top Layer"- Dead keratinocytes o Stratum Lucidum: "Clear Layer"- Colorless protein eleidin o Stratum Granulosum: "Thin Layer"- granular layer o Stratum Spinosum: "Spiny Layer"- Thickest layer, keratinocytes, immune dendritic cells, sensory cells o Stratum Basale: "Basal Layer"- Bottom layer; contains melanocytes. Dermis: Directly below epidermis; mostly connective tissue ● Contains blood vessels ● Sensory receptors ● Hair follicles ● Sebaceous glands ● Sweat glands ● Elastin and Collagen fibers Hypodermis/SubQ: Connective tissue ● Binds the skin to underlying muscle ● Fat deposits cushion and insulate the body Glands Exocrine: Secrete substances into ducts ● Holocrine: secretory products; whole cells; connected to hair follicle o Sebaceous Glands: secrete sebum: an oily mixture of lipids and proteins; waterproofs skin, protects from pathogens ● Eccrine: Not connected to hair follicle, activated by high body temperature, located throughout the body. A type of sweat gland (sudoriferous gland) in thermoregulation. o Secrete a salty solution of electrolytes and water ▪ NaCl ▪ KHCO3 TEAS 6 Science ▪ Glucose ▪ Antimicrobial Peptides ● Apocrine: Secrete an oily solution (fatty acids, triglycerides, and proteins) o Located in: ▪ Armpits ▪ Groin ▪ Palms ▪ Soles of feet o Secrete (sweat) during anxiety or stress o Body Odor forms from bacteria feeding on apocrine sweat Urinary System Kidney (2): Regulates fluid balance and filters waste from blood ● Receive blood from renal artery (extension of aorta) ● Filter blood ● Reabsorb need materials ● Excrete waste and water via urine ● Renal Cortex: Outer Layer o Contains ~1 million Nephrons (filters) o Glomerulus: Capillary in nephron o Bowman's Capsule: encapsulates the glomerulus ● Renal Medulla: Middle Layer o Proximal Convoluted Tubule: Water, glucose, ions, and other organic molecules are reabsorbed back into the blood stream. o Distal Convoluted Tubule: Urea and drugs are removed from blood.

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TEAS 6 Science Anatomy and Physiology Guide.


ANATOMY AND PHYSIOLOGY
Endocrine System
Gland/Organ Hormone Secreted Function

Hypothalamus Releasing/Inhibiting hormones Stimulate Pituitary

Anterior Pituitary (base of Adrenocorticotropic Hormone (ACTH) Stimulate adrenal cortex to secrete
brain; controls growth and glucocorticoids
development
Thyroid Stimulating Hormone (TSH) Stimulate the Thyroid gland

Follicle Stimulating Hormone (FSH) Stimulates production of ova (females) and
sperm (males)

Luteinizing Hormone (LH) Stimulates Ovaries (females) and Testes
(males)

Prolactin Stimulates milk production

Growth Hormone (GH) Stimulates growth (bones) and metabolic
functions

Posterior Pituitary (back of Antidiuretic Hormone (ADH) Promotes retention of water by the kidneys
anterior pituitary)
Oxytocin Stimulates contraction of uterus and mammary
gland cells

Pineal Gland (center of Melatonin Sleep cycles; biorhythms
brain)

Thyroid (neck; hormones Triiodothyronine (T3) Metabolism
regulate growth,
Thyroxine (T4) Metabolism and temperature
development, and
metabolism) Calcitonin Inhibits release of Calcium from bones

Parathyroid (4 glands on Parathyroid Hormone (PTH) Stimulates release of calcium from bones, back
Thyroid) into blood.

Thymus (lymphoid organ Thymosin Stimulates T-Cell Development
that produces T-Cells)

Adrenal Glands (Above See below See below
Kidneys; regulate HR, BP,
and other functions)

Adrenal Cortex (stimulates Cortisol/Glucocorticoids Stress response; Increase blood glucose,
fight or flight response) Decrease immune response; metabolism

Aldosterone Regulates Na content in blood

Adrenal Medulla (stimulates Epinephrine Fight
fight or flight response)
Norepinephrine Flight

Ovaries (female gonads) Estrogen Stimulates egg maturation, controls 2ndary sex

,TEAS 6 Science


characteristics

Progesterone Prepares uterus to receive fertilized egg

Testes (male gonads) Testosterone Regulates sperm production and 2ndary sex
characteristics

Kidneys Erythropoietin Response to cellular hypoxia

Renin Promotes production of Angiotensin

Liver Angiotensin II Vasoconstriction, Increase BP

Pancreas Glucagon (Alpha Cells) Increase blood glucose

Insulin (Beta Cells) Decrease blood glucose

Stomach Gastrin Response to food; stimulates production of
gastric juices

Intestine Secretin Response to acidity in small intestine;
stimulates secretion by liver and pancreas

Cholecystokinin Production of Bile Salts

Heart Atrial Natriuretic Peptide (ANP) Increase renal Na excretion, decrease ECF




Gastrointestinal System
Enzyme Production site Release site

Carbs Salivary Amylase Salivary Glands Mouth

Pancreatic Amylase Pancreas Small Intestine

Maltase Small Intestine Small Intestine

Protein Pepsin Chief Cells (gastric gland) Stomach

Trypsin Pancreas Small Intestine

, TEAS 6 Science


Peptidases Small Intestine Small Intestine

Nucleic Acids Nuclease Pancreas Small Intestine

Nucleosidase Pancreas Small Intestine

Lipids Lipase Pancreas Small Intestine

Bile Salt Liver→Gallbladder Small Intestine


*Bile is technically not an enzyme, but a salt that emulsifies lipid into fatty droplets.
Chief Cells: Covert pepsinogen to pepsin
Goblet Cells: Mucus secretions
Parietal Cells: HCl production
Peyer's Patches: Lymphatic Tissue found in Ileum to protect GI tract from pathogens

Integumentary System
Epidermis: Most superficial layer of skin; entirely epithelial cells

● Does NOT contain blood vessels
● 5 layers
o Stratum Corneum: "Top Layer"- Dead keratinocytes
o Stratum Lucidum: "Clear Layer"- Colorless protein eleidin
o Stratum Granulosum: "Thin Layer"- granular layer
o Stratum Spinosum: "Spiny Layer"- Thickest layer, keratinocytes, immune dendritic
cells, sensory cells
o Stratum Basale: "Basal Layer"- Bottom layer; contains melanocytes.

Dermis: Directly below epidermis; mostly connective tissue

● Contains blood vessels
● Sensory receptors
● Hair follicles
● Sebaceous glands
● Sweat glands
● Elastin and Collagen fibers

Hypodermis/SubQ: Connective tissue

● Binds the skin to underlying muscle
● Fat deposits cushion and insulate the body

Glands

Exocrine: Secrete substances into ducts

● Holocrine: secretory products; whole cells; connected to hair follicle
o Sebaceous Glands: secrete sebum: an oily mixture of lipids and proteins;
waterproofs skin, protects from pathogens
● Eccrine: Not connected to hair follicle, activated by high body temperature, located
throughout the body. A type of sweat gland (sudoriferous gland) in thermoregulation.
o Secrete a salty solution of electrolytes and water
▪ NaCl
▪ KHCO3

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