Statins (HMG-CoA Reductase Inhibitors) Nursing Pharmacology (NCLEX Quiz 2022)

1. A patient is prescribed Pravastatin. This medication is known as a ______________________? A. Fibric Acid Derivative B. Bile-acid Sequestrant C. HMG-CoA Reductase Inhibitor D. Cholesterol Absorption Inhibitor The answer is C: HMG-CoA Reductase Inhibitor. Pravastatin is a STATIN medication which is part of the HMG-CoA Reductase Inhibitor family. 2. Your patient is prescribed a statin medication for the treatment of hyperlipidemia. What medication below may increase the patient’s risk of developing rhabdomyolysis if taken with a statin? A. Ezetimibe B. Gemfibrozil C. Cholestyramine D. Colesevelam The answer is B. The usage of fibric acid derivatives (fibrates….such as Gemfibrozil or Fenofibrate) and statins together can increase the risk of rhabdomyolysis (break down of skeletal muscle which leads to renal failure).