Chamberlain College of Nursing
NR283 Pathophysiology
Worksheet 2
NR283 Worksheet 2.
Questions:
1. Define epidermis, dermis, and subcutaneous tissue.
Epidermis: Consists of 5 layers that vary in thickness @ different areas of the body; no blood
vessels or nerves are present; contains melanocytes (specialized pigment-producing cells);5
layers include: stratum basale (innermost layer located on the basement membrane and only
layer where mitosis occurs), stratum spinosum, stratum granulosum, stratum lucidum (present
primarily in thick skin), and the stratum corneum (outer most layer).
Dermis: A thick layer of connective tissue that includes elastic and collagen fibers and varies in
thickness over the body; provide flexibility and strength in the skin; provides support for the
nerves and blood vessels; contains many sensory receptors for pressure or texture, pain, heat, or
cold
Subcutaneous Tissue (or Hypodermis): Consists of connective tissue, fat, cells, macrophages,
fibroblasts, blood vessels, nerves, and is the base of many of the appendages
2. Define the following;
a. Macule: Small, flat, circumscribed lesion of a different color than the normal skin.
b. Papule: Small, firm, elevated lesion.
NR 283: Worksheet 2 1/2017 TMH 1
,Chamberlain College of Nursing
NR283 Pathophysiology
c. Nodule: Palpable elevated lesion and varies in size.
d. Pustule: Elevated, erythematous lesion, usually containing purulent exudate.
e. Vesicle: Elevated, thin-walled lesion containing clear fluid (blister).
f. Plaque: Large, slightly elevated lesion with a flat surface, often topped by scale.
NR 283: Worksheet 2 1/2017 TMH 2
, Chamberlain College of Nursing
NR283 Pathophysiology
g. Crust: Dry, rough surface or dried exudate or blood.
h. Lichenification: Thick, dry, rough surface (leather-like).
i. Keloid: A raised, irregular, and increasing mass of collagen resulting from excessive scar
tissue formation.
j. Fissure: Small, deep, linear crack or tear in the skin.
k. Ulcer: Cavity with the loss of tissue from the epidermis and dermis and often consists of
weeping or bleeding.
l. Erosion: Shallow, moist cavity in the epidermis.
m. Comedone: A mass of sebum, keratin, and debris blocking the opening of a hair follicle.
NR 283: Worksheet 2 1/2017 TMH 3
NR283 Pathophysiology
Worksheet 2
NR283 Worksheet 2.
Questions:
1. Define epidermis, dermis, and subcutaneous tissue.
Epidermis: Consists of 5 layers that vary in thickness @ different areas of the body; no blood
vessels or nerves are present; contains melanocytes (specialized pigment-producing cells);5
layers include: stratum basale (innermost layer located on the basement membrane and only
layer where mitosis occurs), stratum spinosum, stratum granulosum, stratum lucidum (present
primarily in thick skin), and the stratum corneum (outer most layer).
Dermis: A thick layer of connective tissue that includes elastic and collagen fibers and varies in
thickness over the body; provide flexibility and strength in the skin; provides support for the
nerves and blood vessels; contains many sensory receptors for pressure or texture, pain, heat, or
cold
Subcutaneous Tissue (or Hypodermis): Consists of connective tissue, fat, cells, macrophages,
fibroblasts, blood vessels, nerves, and is the base of many of the appendages
2. Define the following;
a. Macule: Small, flat, circumscribed lesion of a different color than the normal skin.
b. Papule: Small, firm, elevated lesion.
NR 283: Worksheet 2 1/2017 TMH 1
,Chamberlain College of Nursing
NR283 Pathophysiology
c. Nodule: Palpable elevated lesion and varies in size.
d. Pustule: Elevated, erythematous lesion, usually containing purulent exudate.
e. Vesicle: Elevated, thin-walled lesion containing clear fluid (blister).
f. Plaque: Large, slightly elevated lesion with a flat surface, often topped by scale.
NR 283: Worksheet 2 1/2017 TMH 2
, Chamberlain College of Nursing
NR283 Pathophysiology
g. Crust: Dry, rough surface or dried exudate or blood.
h. Lichenification: Thick, dry, rough surface (leather-like).
i. Keloid: A raised, irregular, and increasing mass of collagen resulting from excessive scar
tissue formation.
j. Fissure: Small, deep, linear crack or tear in the skin.
k. Ulcer: Cavity with the loss of tissue from the epidermis and dermis and often consists of
weeping or bleeding.
l. Erosion: Shallow, moist cavity in the epidermis.
m. Comedone: A mass of sebum, keratin, and debris blocking the opening of a hair follicle.
NR 283: Worksheet 2 1/2017 TMH 3
