MOLECULAR GENETICS AND BIOTECHNOLOGY
BTEC 3302 (21709) – 3 Credits
Fall 2019
Instructor: Sivakumar Ganapathy, Ph.D.
Class schedule: Monday and Wednesday 9:00 am - 10:30 am, Room # SAB 203, Sugar Land campus
Office Hours: Sugar Land campus: Monday and Wednesday 12:00 noon -1:30 pm or by appointment
Office: Sugar Land campus: SAB, Room # 215
Email: All communications should be via blackboard email
Class website: http://www.uh.edu/blackboard/ - Login with user ID and password
IMPORTANT DATES:
Last day to drop with no grade: September 04
Last day to drop with a W: October 31
Final Exam (subject to change) November 25, Monday, 9:00 am – 10:30 am, Room # SAB 203
PREREQUISITE(S): Required BIOL 1361/1161, 1362/1162, CHEM 1332, BTEC 1322.
COURSE DESCRIPTION: Overview of molecular genetics and biology as applicable to molecular
biotechnology. Discussion includes transmission-, human- and medical genetics; heterologous protein
production; primary and secondary metabolisms and synthetic biotechnology, and the impact of
bioengineering solutions in economic and biotech industry contexts.
LEARNING OBJECTIVES:
This course provides a broad overview of molecular genetics & advance biotechnology with an
emphasis on how the metabolism of industrially relevant organisms operates, how existing
metabolic pathways can be altered, and how novel metabolic pathways can be introduced in
microorganisms/plants with the use of synthetic biotechnology.
This course is designed for undergraduates who have an interest in metabolic engineering at the
cellular network level.
Students will be introduced to the field of synthetic biotechnology and its application in
protein/metabolic engineering.
Students will understand the basic principles of operation of regulation at the cellular level,
including metabolic, signaling and gene networks; discover how cellular networks can be
reengineered with gene editing.
A special focus is given to pathways leading to industrially relevant products like small
molecules, industrial enzymes, and pharmaceutical proteins.
Overarching objective is to learn advanced technologies in genetic and metabolic engineering.
The broad education is necessary to understand the impact of bioengineering solutions in a
global, economic, environmental, and societal context.
1
This study source was downloaded by 100000840304359 from CourseHero.com on 02-14-2022 04:00:59 GMT -06:00
https://www.coursehero.com/file/53219212/BTEC-3302-Fall-19-21709-Syllabus4pdf/
, RECOMMENDED READING:
For genetics: Mastering Genetics (http://www.masteringgenetics.com online access only)
For molecular biology and biotechnology:
Watson, JD, Baker, TA, Bell SP, Gann, A, Levin, M, Losick R. 2008. Molecular biology of the gene, Sixth
edition, Cold Spring Harbor Laboratory Press.
Glick, BR, Pasternak, JJ, and Patten, CL. 2010. Molecular Biotechnology: Principles and Applications of
Recombinant DNA, 4th edition. ASM Press.
Much of the student presentation material will come from journals such as Nature Biotechnology,
Trends in Biotechnology, Nature, Science and others. These will be posted on the blackboard.
BTEC Program/Student Learning Outcomes
Students will able to gain a comprehensive understanding of the molecular genetics,
biotechnological principles and its applications in agriculture, food, healthcare, pharmaceutical
and bioenergy sectors
Students will possess the technical background knowledge required to understand
chromosomal basis of heredity, transmission-, human-, medical-genetics and cancer biology
Students will possess hands-on molecular biotechnology skills such as DNA replication,
transcription, translation and protein necessary for supporting biotechnology research activity
Students will show understanding their skills and knowledge of gene regulations in prokaryotes
and eukaryotes for biotechnology industry
Students will able to demonstrate the ability to apply research strategies to gene transfer in
bacteria, bacteriophages, baculovirus, animal and plant as well as manipulation of gene
expressions in prokaryotes and heterologous protein production in eukaryotic cells
Students will be able to demonstrate the ability to communicate effectively metabolomics, gene
editing and biopharming with appropriate regulatory agency or pharmaceutical industry
Students will show understanding primary and secondary metabolism and pathway engineering
Students will be able to demonstrate how synthetic biotechnology differs from traditional
genetic engineering
Students will be able to demonstrate metabolic engineering research presentation and solve
industrial biotechnology problems
Students will able to identify, analyze and communicate ethical and societal issues associated
with biotechnological advances
Youtube, virtual labs, and research articles-based homework can help students strengthen their
molecular biotechnology skills
Important Note: Electronic devices such as cell phone, playing or recording devices; text messaging and
emails are not allowed to use during the class and exams. Please show blackboard Exam submission
confirmation before leave the classroom. Failure to follow these instructions will result in an automatic F
grade. Do not post this class materials, syllabus, class PowerPoints (PPT), quizzes, homework’s, exams
and presentations, etc. in internet or any social media. Students violating this policy, disciplinary
actions (s) will be taken as necessary. Drop this course, if you are unable to follow the class policy.
Minimum passing grade is C- and minimum grade of C- is required all prerequisite(s).
2
This study source was downloaded by 100000840304359 from CourseHero.com on 02-14-2022 04:00:59 GMT -06:00
https://www.coursehero.com/file/53219212/BTEC-3302-Fall-19-21709-Syllabus4pdf/
BTEC 3302 (21709) – 3 Credits
Fall 2019
Instructor: Sivakumar Ganapathy, Ph.D.
Class schedule: Monday and Wednesday 9:00 am - 10:30 am, Room # SAB 203, Sugar Land campus
Office Hours: Sugar Land campus: Monday and Wednesday 12:00 noon -1:30 pm or by appointment
Office: Sugar Land campus: SAB, Room # 215
Email: All communications should be via blackboard email
Class website: http://www.uh.edu/blackboard/ - Login with user ID and password
IMPORTANT DATES:
Last day to drop with no grade: September 04
Last day to drop with a W: October 31
Final Exam (subject to change) November 25, Monday, 9:00 am – 10:30 am, Room # SAB 203
PREREQUISITE(S): Required BIOL 1361/1161, 1362/1162, CHEM 1332, BTEC 1322.
COURSE DESCRIPTION: Overview of molecular genetics and biology as applicable to molecular
biotechnology. Discussion includes transmission-, human- and medical genetics; heterologous protein
production; primary and secondary metabolisms and synthetic biotechnology, and the impact of
bioengineering solutions in economic and biotech industry contexts.
LEARNING OBJECTIVES:
This course provides a broad overview of molecular genetics & advance biotechnology with an
emphasis on how the metabolism of industrially relevant organisms operates, how existing
metabolic pathways can be altered, and how novel metabolic pathways can be introduced in
microorganisms/plants with the use of synthetic biotechnology.
This course is designed for undergraduates who have an interest in metabolic engineering at the
cellular network level.
Students will be introduced to the field of synthetic biotechnology and its application in
protein/metabolic engineering.
Students will understand the basic principles of operation of regulation at the cellular level,
including metabolic, signaling and gene networks; discover how cellular networks can be
reengineered with gene editing.
A special focus is given to pathways leading to industrially relevant products like small
molecules, industrial enzymes, and pharmaceutical proteins.
Overarching objective is to learn advanced technologies in genetic and metabolic engineering.
The broad education is necessary to understand the impact of bioengineering solutions in a
global, economic, environmental, and societal context.
1
This study source was downloaded by 100000840304359 from CourseHero.com on 02-14-2022 04:00:59 GMT -06:00
https://www.coursehero.com/file/53219212/BTEC-3302-Fall-19-21709-Syllabus4pdf/
, RECOMMENDED READING:
For genetics: Mastering Genetics (http://www.masteringgenetics.com online access only)
For molecular biology and biotechnology:
Watson, JD, Baker, TA, Bell SP, Gann, A, Levin, M, Losick R. 2008. Molecular biology of the gene, Sixth
edition, Cold Spring Harbor Laboratory Press.
Glick, BR, Pasternak, JJ, and Patten, CL. 2010. Molecular Biotechnology: Principles and Applications of
Recombinant DNA, 4th edition. ASM Press.
Much of the student presentation material will come from journals such as Nature Biotechnology,
Trends in Biotechnology, Nature, Science and others. These will be posted on the blackboard.
BTEC Program/Student Learning Outcomes
Students will able to gain a comprehensive understanding of the molecular genetics,
biotechnological principles and its applications in agriculture, food, healthcare, pharmaceutical
and bioenergy sectors
Students will possess the technical background knowledge required to understand
chromosomal basis of heredity, transmission-, human-, medical-genetics and cancer biology
Students will possess hands-on molecular biotechnology skills such as DNA replication,
transcription, translation and protein necessary for supporting biotechnology research activity
Students will show understanding their skills and knowledge of gene regulations in prokaryotes
and eukaryotes for biotechnology industry
Students will able to demonstrate the ability to apply research strategies to gene transfer in
bacteria, bacteriophages, baculovirus, animal and plant as well as manipulation of gene
expressions in prokaryotes and heterologous protein production in eukaryotic cells
Students will be able to demonstrate the ability to communicate effectively metabolomics, gene
editing and biopharming with appropriate regulatory agency or pharmaceutical industry
Students will show understanding primary and secondary metabolism and pathway engineering
Students will be able to demonstrate how synthetic biotechnology differs from traditional
genetic engineering
Students will be able to demonstrate metabolic engineering research presentation and solve
industrial biotechnology problems
Students will able to identify, analyze and communicate ethical and societal issues associated
with biotechnological advances
Youtube, virtual labs, and research articles-based homework can help students strengthen their
molecular biotechnology skills
Important Note: Electronic devices such as cell phone, playing or recording devices; text messaging and
emails are not allowed to use during the class and exams. Please show blackboard Exam submission
confirmation before leave the classroom. Failure to follow these instructions will result in an automatic F
grade. Do not post this class materials, syllabus, class PowerPoints (PPT), quizzes, homework’s, exams
and presentations, etc. in internet or any social media. Students violating this policy, disciplinary
actions (s) will be taken as necessary. Drop this course, if you are unable to follow the class policy.
Minimum passing grade is C- and minimum grade of C- is required all prerequisite(s).
2
This study source was downloaded by 100000840304359 from CourseHero.com on 02-14-2022 04:00:59 GMT -06:00
https://www.coursehero.com/file/53219212/BTEC-3302-Fall-19-21709-Syllabus4pdf/
