Iron-deficiency anemia
A condition in which blood lacks adequate healthy red blood cells. Red blood cells
carry oxygen to the body's tissues. As the name implies, iron deficiency anemia is
due to insufficient iron.
Pernicious anemia
Pernicious anemia is an autoimmune condition that affects your stomach. An
autoimmune condition means your immune system, the body's natural defence
system that protects against illness and infection, attacks your body's healthy cells.
Vitamin B12 is combined with a protein called intrinsic factor in your stomach.
Aplastic anemia
Aplastic anemia is a condition that occurs when your body stops producing enough
new blood cells. The condition leaves you fatigued and more prone to infections
and uncontrolled bleeding.
Hemo- lytic anemia
Hemolytic anemia is a disorder in which red blood cells are destroyed faster than
they can be made. The destruction of red blood cells is called hemolysis.
Effect of nutritional anemias on CBC
With anemia, some of the components of the CBC that may show abnormal results
include: RBC count—typically low. Hemoglobin—low. Hematocrit—low.
A low level of hemoglobin or hematocrit is a sign of anemia. The normal range of
these levels varies in certain racial and ethnic populations. Your doctor can explain
your test results to you. The CBC also checks the number of red blood cells, white
blood cells, and platelets in your blood.
Absorption of iron in our body
The absorption of most dietary iron occurs in the duodenum and proximal jejunum
and depends heavily on the physical state of the iron atom. At physiological pH,
iron exists in the oxidized, ferric (Fe3+) state. To be absorbed, iron must be in the
ferrous (Fe2+) state or bound by a protein such as heme.
Enhancers and inhibitors of iron