Immune System
7. Polymorphonuclear leukocytes (or PMNs)
1. Large parasites such as helminthes may be killed
extracellularly by the action of A. can be attracted to the site of an infection following
activation of complement
A. basophils B. are derived from bone marrow stem cells
B. monocytes C. are a type of phagocyte that can engulf and kill bacteria
C. eosinophils D. all of the above
D. neutrophils
2. Which of the following is correct for CD8 T cells? 8. Major Histo Compatibility Complex (MHC) is a collection
of genes arrayed on
A. CD8 T cells only recognize virus-infected cells
B. CD8 T cell receptor recognizes epitopes that are also A. chromosome 21 in man, chromosome 6 in mice
commonly recognized by B cells B. chromosome 6 in man, chromosone 21 in mice
C. In the thymus, CD8 T cells undergo positive selection C. chromosome 17in man, chromosome 6 in mice
only, whereas CD4 T cells undergo negative selection only D. chromosome 6 in man, chromosome 17 in mice
D. CD8 T cells can kill individual virus-infected cells in a
contact dependent fashion 9. CD8 surface antigen is present in
3. Passive immunization is done for A. cytotoxic T cells
B. suppresssor T cells
A. tuberculosis C. both (a) and (b)
B. diphtheria D. none of these
C. enteric fever
D. all of these 10. Treatment with bacterial endotoxins results blast
formation in
4. Which of the following is correct for isoantigens?
A. B cells
A. They are antigens found in all members of different B. T cells
species C. monocytes
B. They are antigens found in some members of a species D. none of these
C. They are antigens found in all members of a species
D. They are antigens found in some members of different 11. Cytotoxic T-cells can be recognized by which of the
species following cell surface marker?
5. Numerous antibodies can be prepared, against one A. CD4
antigen, each binds to unique epitopes. How is this B. CD7
antibody diversity generated? C. CD8
D. CD9
A. By rearrangements of the DNA encoding the variable
regions of the heavy and light chains 12. Which is not an antigen-presenting cell (or APC)?
B. By the combination of different heavy and light chains
that form the antigen binding site A. B cell
C. Antibody proteins can physically change their shape to B. Polymorphonuclear leukocyte (or PMN)
bind different epitopes C. Dendritic cell
D. Both (a) and (b) D. All of the above
6. Which of the following expresses CD3 surface antigen? 13. Chemically an antigen may be
A. Granulocytes A. lipid
B. T cells B. protein
C. Monocytes C. polysaccharide
D. B cells D. any of these
7. Polymorphonuclear leukocytes (or PMNs)
1. Large parasites such as helminthes may be killed
extracellularly by the action of A. can be attracted to the site of an infection following
activation of complement
A. basophils B. are derived from bone marrow stem cells
B. monocytes C. are a type of phagocyte that can engulf and kill bacteria
C. eosinophils D. all of the above
D. neutrophils
2. Which of the following is correct for CD8 T cells? 8. Major Histo Compatibility Complex (MHC) is a collection
of genes arrayed on
A. CD8 T cells only recognize virus-infected cells
B. CD8 T cell receptor recognizes epitopes that are also A. chromosome 21 in man, chromosome 6 in mice
commonly recognized by B cells B. chromosome 6 in man, chromosone 21 in mice
C. In the thymus, CD8 T cells undergo positive selection C. chromosome 17in man, chromosome 6 in mice
only, whereas CD4 T cells undergo negative selection only D. chromosome 6 in man, chromosome 17 in mice
D. CD8 T cells can kill individual virus-infected cells in a
contact dependent fashion 9. CD8 surface antigen is present in
3. Passive immunization is done for A. cytotoxic T cells
B. suppresssor T cells
A. tuberculosis C. both (a) and (b)
B. diphtheria D. none of these
C. enteric fever
D. all of these 10. Treatment with bacterial endotoxins results blast
formation in
4. Which of the following is correct for isoantigens?
A. B cells
A. They are antigens found in all members of different B. T cells
species C. monocytes
B. They are antigens found in some members of a species D. none of these
C. They are antigens found in all members of a species
D. They are antigens found in some members of different 11. Cytotoxic T-cells can be recognized by which of the
species following cell surface marker?
5. Numerous antibodies can be prepared, against one A. CD4
antigen, each binds to unique epitopes. How is this B. CD7
antibody diversity generated? C. CD8
D. CD9
A. By rearrangements of the DNA encoding the variable
regions of the heavy and light chains 12. Which is not an antigen-presenting cell (or APC)?
B. By the combination of different heavy and light chains
that form the antigen binding site A. B cell
C. Antibody proteins can physically change their shape to B. Polymorphonuclear leukocyte (or PMN)
bind different epitopes C. Dendritic cell
D. Both (a) and (b) D. All of the above
6. Which of the following expresses CD3 surface antigen? 13. Chemically an antigen may be
A. Granulocytes A. lipid
B. T cells B. protein
C. Monocytes C. polysaccharide
D. B cells D. any of these
