ch. 48 - Immunosuppressant Drugs
WHAT WE NEED TO KNOW FOR:
Chapter 48: Immunosuppressant Drugs - Chapter 48: Immunosuppressant
Drugs
1. Purpose of cytokine
suppression in immunosuppression
2. Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results
3. Cyclosporine
a. Mechanism of action
b. Adverse effects
c. Contraindication
d. Potential medication and food interactions
Purpose of cytokine
suppression in immunosuppression -
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - Antimetabolites (e.g., azathioprine,
mycophenolate) inhibit cell proliferation.
, ch. 48 - Immunosuppressant Drugs
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - note any s/sx of infection as well as any bleeding
tendencies due to the potential for drug-related leukopenia and
thrombocytopenia.
Leukopenia is a potential adverse effect of azathioprine therapy, so white
blood cells need to be monitored.
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - With azathioprine, assess WBC and platelet count.
note any s/sx of infection as well as any bleeding tendencies due to the
potential for drug-related leukopenia and thrombocytopenia.
When monitoring a patient who is on immunosuppressant therapy with
azathioprine (Imuran), the nurse will monitor which laboratory results? -
White blood cell (leukocyte) count
Leukopenia is a potential adverse effect of azathioprine therapy, so white
blood cells need to be monitored.
Cyclosporine
a. Mechanism of action
WHAT WE NEED TO KNOW FOR:
Chapter 48: Immunosuppressant Drugs - Chapter 48: Immunosuppressant
Drugs
1. Purpose of cytokine
suppression in immunosuppression
2. Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results
3. Cyclosporine
a. Mechanism of action
b. Adverse effects
c. Contraindication
d. Potential medication and food interactions
Purpose of cytokine
suppression in immunosuppression -
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - Antimetabolites (e.g., azathioprine,
mycophenolate) inhibit cell proliferation.
, ch. 48 - Immunosuppressant Drugs
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - note any s/sx of infection as well as any bleeding
tendencies due to the potential for drug-related leukopenia and
thrombocytopenia.
Leukopenia is a potential adverse effect of azathioprine therapy, so white
blood cells need to be monitored.
Azathioprine
a. Mechanism of action
b. Adverse effects
c. Monitoring lab results - With azathioprine, assess WBC and platelet count.
note any s/sx of infection as well as any bleeding tendencies due to the
potential for drug-related leukopenia and thrombocytopenia.
When monitoring a patient who is on immunosuppressant therapy with
azathioprine (Imuran), the nurse will monitor which laboratory results? -
White blood cell (leukocyte) count
Leukopenia is a potential adverse effect of azathioprine therapy, so white
blood cells need to be monitored.
Cyclosporine
a. Mechanism of action
