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NR507 Week 3 Quiz (2 Versions, Latest-2022)/ NR 507 Week 3 Quiz: Advanced Pathophysiology: Chamberlain College of Nursing |100% Correct Answers, Already Graded “A”|

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NR507 Week 3 Quiz (2 Versions, Latest-2022)/ NR 507 Week 3 Quiz: Advanced Pathophysiology: Chamberlain College of Nursing |100% Correct Answers, Already Graded “A”| NR507 Week 3 Quiz (Latest): Advanced Pathophysiology: Chamberlain College of Nursing NR 507 Week 3 (Latest): Advanced Pathophysiology: Chamberlain College of Nursing 1. Question : The underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12. microcytic pernicious hypochromic hemolytic Question 2. Question : Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia? Iron deficiency Pernicious Sideroblastic Aplastic Question 3. Question : In hemolytic anemia, jaundice occurs only when erythrocytes are destroyed in the spleen. heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin. the patient has elevations in aspartate transaminase (AST) and alanine transaminase (ALT). the erythrocytes are coated with an immunoglobulin. Question 4. Question : Which anemia produces small, pale erythrocytes? Folic acid Hemolytic Iron deficiency Pernicious Question 5. Question : A woman complains of chronic gastritis, fatigue, weight loss, and tingling in her fingers. Laboratory findings show low hemoglobin and hematocrit levels, and a high mean corpuscular volume. These findings are consistent with _____ anemia. folate deficiency pernicious iron deficiency aplastic Question 6. Question : What is the pathophysiologic process of aplastic anemia? Autoimmune disease against hematopoiesis by activated cytotoxic T cells Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells Autoimmune disease against hematopoiesis by activated immunoglobulins Inherited genetic disorder with recessive X-linked transmission Question 7. Question : Which proinflammatory cytokines are responsible for the development and maintenance of DIC? Granulocyte colony-stimulating factor (G-CSF); IL-2, IL-4, and IL-10; and IFN-g Granulocyte-macrophage colony-stimulating factor (GM-CSF); IL-3, IL-5, and IL-9, and IFN-g Macrophage colony-stimulating factor (M-CSF); IL-7, IL-11, and IL-14; and PAF TNF-a; IL-1, IL-6, and IL-8; and PAF Question 8. Question : Heparin-induced thrombocytopenia (HIT) is described as a(n) IgG immune-mediated adverse drug reaction that reduces circulating platelets. hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body’s needs. IgE-mediated allergic drug reaction that reduces circulating platelets. cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells. Question 9. Question : Which of the following is a description consistent with chronic lymphocytic leukemia (CLL)? There are defects in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein. The bone marrow and peripheral blood are characterized by leukocytosis and a predominance of blast cells. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes. There is failure of B cells to mature into plasma cells that synthesize immunoglobulins. The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL. Question 10. Question : What is the most common cause of vitamin K deficiency? Administration of warfarin (Coumadin) Total parenteral nutrition (TPN) with antibiotic therapy An IgG-mediated autoimmune disorder Liver failure Question 11. Question : Idiopathic thrombocytopenic purpura (ITP) is an autoimmune process involving antibodies against neutrophils. eosinophils. platelets. basophils. Question 12. Question : The sickle cell trait differs from sickle cell disease in that the child with sickle cell trait inherited normal hemoglobin A from one parent and Hb S from the other parent, whereas the child with sickle cell disease has Hb S from both parents. has a mild form of sickle cell disease that causes sickling during fever and infection, but not during acidosis or hypoxia, whereas the child with sickle cells disease develops sickling during each of these conditions. has a milder form of the disease that is characterized by vaso-occlusive crises and is believed to result from higher hemoglobin values and viscosity. has the mildest form of the disease with normal hemoglobin and hemoglobin F, which prevents sickling. Question 13. Question : In a full-term infant, the normal erythrocyte life span is _____ days, whereas the adult is _____ days. 30 to 50; 80 60 to 80; 120 90 to 110; 140 120 to 130; 150 Question 14. Question : What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the brain? Kernicterus Icterus neonatorum Jaundice Icterus gravis neonatorum Question 15. Question : The type of anemia that occurs as a result of thalassemia is microcytic, hypochromic. microcytic, normochromic. macrocytic, hyperchromic. macrocytic, normochromic. Question 16. Question : G6PD and sickle cell disease are inherited X-linked recessive disorders. inherited autosomal recessive disorders. disorders initiated by hypoxemia and acidosis. diagnosed equally in men and women. Question 17. Question : An individual who is demonstrating elevated levels of troponin, creatine kinase (CK), and lactic dehydrogenase (LDH) is exhibiting indicators associated with: myocardial ischemia. hypertension. myocardial infarction (MI). coronary artery disease. Question 18. Question : Which of the following is manufactured by the liver and primarily contains cholesterol and protein? Very-low-density lipoproteins (VLDLs) Low-density lipoproteins (LDLs) High-density lipoproteins (HDLs) Triglycerides (TGs) Question 19. Question : Atherosclerosis causes an aneurysm by causing ischemia of the intima. increasing nitric oxide. eroding the vessel wall. obstructing the vessel. Question 20. Question : Cardiac cells can withstand ischemic conditions and still return to a viable state for how many minutes? 10 15 20 25 Question 21. Question : An infant has a loud, harsh, holosystolic murmur and systolic thrill that can be detected at the left lower sternal border that radiates to the neck. These clinical findings are consistent with which congenital heart defect? Atrial septal defect (ASD) Ventricular septal defect (VSD) Patent ductus arteriosus (PDA) Atrioventricular canal (AVC) defect Question 22. Question : The foramen ovale is covered by a flap that creates a check valve allowing blood to flow unidirectionally from the _____ to the _____. right atrium; right ventricle right ventricle; left ventricle right atrium; left atrium left atrium; left ventricle Question 23. Question : What is the most important clinical manifestation of aortic coarctation in the neonate? Congestive heart failure (CHF) Cor pulmonale Pulmonary hypertension Cerebral hypertension Question 24. Question : Which heart defect produces a systolic ejection murmur at the right upper sternal border that transmits to the neck and left lower sternal border with an occasional ejection click? Coarctation of the aorta Pulmonic stenosis Aortic stenosis Hypoplastic left heart syndrome Question 25. Question : When does systemic vascular resistance in infants begin to rise? One month before birth During the beginning stage of labor One hour after birth Once the placenta is removed from circulation

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,Q. 4.4. A physical assessment of a 28-year-old female patient indicates that her blood pressure in her
legs is lower than that in her arms & that her brachial pulse is weaker in her left arm than in her right.
In addition, her femoral pulses are weak bilaterally. Which of the following possibilities would her care
provider be most likely to suspect? (Points : 0.4)

Pheochromocytoma
Essential hypertension
Coarctation of the aorta
An adrenocortical disorder




Q. 5.5. A 6-year-old boy has been brought to the emergency department by ambulance after his
mother discovered that his heart rate was “so fast I couldn't even count it.” The child was determined
to be in atrial flutter & his mother is seeking an explanation from the health care team. Which of the
following points should underlie an explanation to the mother? (Points : 0.4)

The child is experiencing a reentry rhythm in his right atrium.
The resolution of the problem is dependent on spontaneous recovery & is resistant to pacing
interventions.
The child is likely to have a normal ECG apart from the rapid heart rate.
The boy's atria are experiencing abnormal sympathetic stimulation.




Q. 6.6. A 66-year-old patient's echocardiogram reveals a hypertrophied left ventricle, normal chamber
volume, & a normal ejection fraction from the heart. What is this patient's most likely
diagnosis? (Points : 0.4)

Mitral valve regurgitation
Aortic valve stenosis
Mitral valve stenosis
Aortic valve regurgitation




Q. 7.7. A 70-year-old male patient presents to the emergency department complaining of pain in his
calf that is exacerbated when he walks. His pedal & popliteal pulses are faintly palpable & his leg distal
to the pain is noticeably reddened. What would his care provider's preliminary diagnosis & anticipated
treatment most likely be?(Points : 0.4)

Acute arterial occlusion that will be treated with angioplasty
Raynaud disease that will require antiplatelet medications
Atherosclerotic occlusive disease necessitating thrombolytic therapy

, Giant cell temporal arteritis that will be treated with corticosteroids




Q. 8.8. A patient in the intensive care unit has a blood pressure of 87/39 & has warm, flushed skin
accompanying his sudden decline in level of consciousness. The patient also has arterial & venous
dilation & a decrease in systemic vascular resistance. What is this patient's most likely
diagnosis? (Points : 0.4)

Hypovolemic shock
Septic shock
Neurogenic shock
Obstructive shock




Q. 9.9. A 31-year-old woman with a congenital heart defect reports episodes of lightheadedness &
syncope, with occasional palpitations. A resting electrocardiogram reveals sinus bradycardia & she is
suspected of having sick sinus syndrome. Which of the following diagnostic methods is the best choice
to investigate the suspicion? (Points : 0.4)

Signal-averaged ECG
Exercise stress testing
Electrophysiologic study
Holter monitoring




Q. 10.10. A nurse practitioner is providing care for several patients on a medical unit of a hospital. In
which of the following patient situations would the nurse practitioner be most likely to rule out
hypertension as a contributing factor? (Points : 0.4)

A 61-year-old man who has a heart valve infection & recurrent fever
An 81-year-old woman who has had an ischemic stroke & has consequent one-sided weakness
A 44-year-old man awaiting a kidney transplant who requires hemodialysis three times per week
A 66-year-old woman with poorly controlled angina & consequent limited activity tolerance




Q. 11.11. A patient is experiencing impaired circulation secondary to increased systemic arterial
pressure. Which of the following statements is the most relevant phenomenon?(Points : 0.4)

Increased preload due to vascular resistance
High afterload because of backpressure against the left ventricle
Impaired contractility due to aortic resistance
Systolic impairment because of arterial stenosis

, Q. 12.12. A number of patients have presented to the emergency department in the last 24 hours with
complaints that are preliminarily indicative of myocardial infarction. Which of the following patients is
least likely to have an ST-segment myocardial infarction (STEMI)? (Points : 0.4)

A 70-year-old woman who is complaining of shortness of breath & vague chest discomfort
A 66-year-old man who has presented with fatigue, nausea& vomiting, & cool, moist skin
A 43-year-old man who woke up with substernal pain that is radiating to his neck & jaw
A 71-year-old man who has moist skin, fever, & chest pain that is excruciating when he moves but
relieved when at rest




Q. 13.13. A formerly normotensive woman, pregnant for the first time, develops hypertension &
headaches at 26 weeks' gestation. Her blood pressure is 154/110 mm Hg & she has proteinuria. What
other labs should be ordered for her? (Points : 0.4)

Plasma angiotensin I & II & renin
Urinary sodium & potassium
Platelet count, serum creatinine, & liver enzymes
Urinary catecholamines & metabolites




Q. 14.14. An older adult female patient has presented with a new onset of shortness of breath, & the
patient's nurse practitioner has ordered measurement of her BNP levels along with other diagnostic
tests. What is the most accurate rationale for the nurse practitioner's choice of blood work? (Points :
0.4)

BNP is released as a compensatory mechanism during heart failure & measuring it can help
differentiate the patient's dyspnea from a respiratory pathology.
BNP is an indirect indicator of the effectiveness of the RAA system in compensating for heart failure.
BNP levels correlate with the patient's risk of developing cognitive deficits secondary to heart failure
& consequent brain hypoxia.
BNP becomes elevated in cases of cardiac asthma, Cheyne-Stokes respirations, & acute pulmonary
edema, & measurement can gauge the severity of pulmonary effects.




Q. 15.15. The nurse practitioner for a cardiology practice is responsible for providing presurgical
teaching for patients who are about to undergo a coronary artery bypass graft. Which of the following
teaching points best conveys an aspect of the human circulatory system? (Points : 0.4)

“Your blood pressure varies widely between arteries & veins, & between pulmonary & systemic

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