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NURP 423 - Exam 3 Study Guide.

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NURP 423 - Exam 3 Study Guide.

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Bacterial infections on skin (usually because areas are already open) caused by MRSA, staph aureus,
Group A strep (pyogenes), Methicillin sensitive staph aureus, less common= pseudomonas, H flu.,
corynebactor

Primary INF:

 Impetigo-primary infection by staph aureus or strep bacterial infection
 Ecthyma-thighs or buttocks-pustular
 Folliculitis-staph – klebsiella-hair follicle gets infected-staph, MRSA- or pseudomonas from water
(pool or hot tub). Folliculitis=TX with clindamycin and Erythromycin (topical).
 Follicular eczema-allergic response
 Cellulitis-group a strep, staph aureus, H. influenza
 Furuncle-boil =use warm compress
 More than one-carbuncle-caused by staph/MRSA

Secondary from open skin (ulcer/abrasion/surg wound/eczema)

 MRSA
 staph aureus
 streptococci
 enterococci
 Anerobes

KNOW DIFFERENCE /B/ primary and secondary inf.

 Methicillin sensitive staph aureus, Strep pyogenes, methicillin resistant staph aureus are the
most common causes of skin infection in the __________ setting.
a) Hospital
b) NSG home
c) Primary care



TX: NON PHARM-

 Chlorhexidine baths, keep clean, warm compresses for pustules, bleach baths, Incise and
drainFIRST-culture to guide antibiotic choice

Impetigo: Bacitracin-not as effective-USE BACTROBAN-

ORAL abo for skin infection-Keflex-cephalosporin, dycloxicilin, Cipro

Pseudomonas? Cipro or beta lactam and macrolide

First class cellulitis-keflex-cephalexin-first gen cephalosporin

 Which of the following is the first line treatment for cellulitis?
a) Vanco
b) Keflex (it’s a cef)
c) Omnicef

,MRSA-give Bactrim in outpatient or clindamycin, linezolid

Decolonization: bouncing around in families-treat everyone-bactroban in nares bid, chlorhexidine wash,
or bleach bath.

Abscesses and Carbuncle-I & D first (Its primary tx for them)

 Incision and drainage is the primary treatment for:
a) Abscess (note that carbuncles need I&D as well)
b) Acne
c) Dematitis


MRSA-Bactrim-4-6mg/kg per dose-START WITHAllergic to Bactrim? Give doxycycline- OR clindamycin

 Treating MRSA in the outpatient setting includes:
a) Azithromycin
b) Amoxicillin
c) Bactrim

Acne-Inflammatory or non-inflammatory-disorder of pylo sebaceous unit-gets plugged-bacteria grows
and causes inflammation> pustule=worse inflame. If cysts=deratologist



Define pustular acne.

Pustular acne refers to the appearance and spread of one of the main lesions of acne: pustules. Pustules
are inflammatory lesions and when left untreated they can morph into nodules. Find out the right
treatment for pustular acne.

 Inflammation is the phase found with:REVIEW ACNE PHASES
a) Pustular acne
b) Dormant acne
c) Cellulitis


These can become cystic, d/t abscess formation, & scarring may occur, then would refer to dermatology



If Pustular acne-inflammation-Treat-non-pharmacological-ask about skin regimen to see if there is a
cause-hair product, moisturizer, conditioning hair, hygiene

 Teach them to gently wash face bid with mild soap-do not scrub or rub
 Med for acne- 1st choice-benzo peroxide topical (a keratolytic)-may cause irritation or scaling-
can give a different form


 Irritation and scaling are side effects of:
a) Keflex
b) Benzoyl peroxide

, c) Rocephin



Meds:

1. Keratolitic-first line, antibacterial, reduce hyperkeritinization
2. Retinoid-Retin-second class A-effective for acne and reverses abnormal keratinization-
3. ATB’s



1. Keratolytic:
 benzyl peroxide-OTC, comes in all kind of forms-acne wash
 Salicylic acid-acne wash
 Axelaic acid
 Sulfur (rarely used d/t odor).
2. Retinoids: causes local irritation that gets better with time-most therapies make the acne
worse before it gets better. Pea sized amount around entire face. Start slow. Once a week.
Then twice a week. Etc.
 Tretinoin (Retin-A): causes local irritationthat gets better with time. MUST BE WORN
WITH SUN SCREEN.
 Differin (Adapalene)- less irritation but more expensive.
 Tazarotene (Tazorac): used when pts have trouble with other options.
3. Topical ATBs: (gel, solution, or lotion) MUST BE USED WITH BENZOYL PEROXIDE TO AVIOD
DRUG RESISTANCE & KERATINIZATION.
 Erythromycin & Clindamycin (Erythromycin, clindamycin. MUST BE used together.)
 Sulfacetamide
4. Oral ATB’s: for severe acne. Give this and send to Derm!
 Tetra, doxy, and mino-cycline
5. ACCUTANE: Severe cystic acne only!!!
 Prego cat X!!!
 Monitor prego test (HCG levels), lipids, depression/mood changes, and OP.
 cause irritation, scaly

Step wise treatment-

 always start with non- pharmacological care > Topical Keratolytic> nightly topical (RETIN-A) not
together with a keratolytic> Topical ATB with item 2 in the AM and item 3 in HS> systemic
ATB>Isotretoin (Accutane)

Infestations:

Scabies-put on Elimite cream at night and then wash clothes and bedding in AM with hot H2O

Pediculosis-Head lice-prometherine-otc-SE: skin irritation and neurotoxicity-if patient does not want
neurotoxin risk, give a lotion-Fear of neurotoxicity-

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