Chapter 1: Immunology: Basic Principles and Applications in the Blood Bank
Test Bank
MULTIPLE CHOICE
1. Select the cell involved in humoral immunity.
a. Neutrophils
b. T lymphocytes
c. B lymphocytes
d. Monocytes
ANS: C
B lymphocytes have the ability to transform into plasma cells to produce antibodies, which is
considered a humoral response.
DIF: Level 2 REF: p. 2
2. Opsonization is a term to describe what process?
a. Lysis of cells
b. Binding to cells or antigens
c. Ingestion of cells
d. Phagocytosis
ANS: B
Opsonization promotes phagocytosis by binding to cells or antigens.
DIF: Level 1 REF: p. 14
3. Select the term that is associated with the B-cell response to antigens.
a. Humoral immunity
b. Cellular immunity
c. Innate immunity
d. Nonspecific immunity
ANS: A
B cells produce antibody, a humoral response.
DIF: Level 2 REF: p. 2
Copyright © 2013, 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 1
, 4. Select the substance that regulates the activity of other cells by binding to specific receptors.
a. Cytokines
b. Complement
c. Immunoglobulins
d. Anaphylatoxin
ANS: A
Cytokines are proteins secreted by cells that regulate the activity of other cells by binding to
specific receptors.
DIF: Level 1 REF: p. 2
5. Which of the following is responsible for the activation of the classic pathway of
complement?
a. Bacteria
b. Foreign proteins
c. Virus
d. Antibody bound to antigen
ANS: D
An antigen-antibody complex activates the classical complement cascade, whereas bacterial
membranes activate the alternative pathway.
DIF: Level 1 REF: p. 13
6. The major histocompatibility complex is located on chromosome 6 and is important in all the
following immune functions except:
a. recognition of nonself.
b. graft rejection.
c. hemolysis.
d. coordination of cellular and humoral immunity.
ANS: C
The major histocompatibility complex codes for molecules on all nucleated tissues and cells
to allow for immune recognition and response to foreign antigens.
DIF: Level 2 REF: p. 19
Copyright © 2013, 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 2
Test Bank
MULTIPLE CHOICE
1. Select the cell involved in humoral immunity.
a. Neutrophils
b. T lymphocytes
c. B lymphocytes
d. Monocytes
ANS: C
B lymphocytes have the ability to transform into plasma cells to produce antibodies, which is
considered a humoral response.
DIF: Level 2 REF: p. 2
2. Opsonization is a term to describe what process?
a. Lysis of cells
b. Binding to cells or antigens
c. Ingestion of cells
d. Phagocytosis
ANS: B
Opsonization promotes phagocytosis by binding to cells or antigens.
DIF: Level 1 REF: p. 14
3. Select the term that is associated with the B-cell response to antigens.
a. Humoral immunity
b. Cellular immunity
c. Innate immunity
d. Nonspecific immunity
ANS: A
B cells produce antibody, a humoral response.
DIF: Level 2 REF: p. 2
Copyright © 2013, 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 1
, 4. Select the substance that regulates the activity of other cells by binding to specific receptors.
a. Cytokines
b. Complement
c. Immunoglobulins
d. Anaphylatoxin
ANS: A
Cytokines are proteins secreted by cells that regulate the activity of other cells by binding to
specific receptors.
DIF: Level 1 REF: p. 2
5. Which of the following is responsible for the activation of the classic pathway of
complement?
a. Bacteria
b. Foreign proteins
c. Virus
d. Antibody bound to antigen
ANS: D
An antigen-antibody complex activates the classical complement cascade, whereas bacterial
membranes activate the alternative pathway.
DIF: Level 1 REF: p. 13
6. The major histocompatibility complex is located on chromosome 6 and is important in all the
following immune functions except:
a. recognition of nonself.
b. graft rejection.
c. hemolysis.
d. coordination of cellular and humoral immunity.
ANS: C
The major histocompatibility complex codes for molecules on all nucleated tissues and cells
to allow for immune recognition and response to foreign antigens.
DIF: Level 2 REF: p. 19
Copyright © 2013, 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 2
