Preceptor Session 10 Key
1. Activated activates PLC which then activates .
a. G-protein, DAG
b. G-protein, calcium
c. G-protein, IP3
d. Two of the above the g-protein activates PLC which activates IP3 and DAG
e. None of the above
2. What does IP3 activate? What does this cause?
a. IP3 binds to calcium channels, allowing calcium to release from the ER. An
example of this is when sperm goes into the egg, it causes a release of
calcium which turns the embryo “on” starting life.
3. Once calcium is released in the PLC pathway, it binds to which changes its
shape so it can become an effector protein to activate other proteins
a. Cyclic AMP
b. Calmodulin
c. Receptor tyrosine kinase
d. Two of these
e. None of these
4. Which type of pathway is responsible for vision (superfast pathway)
a. GPCR pathway
b. Ion channel pathway
c. Enzyme coupled receptor pathway
d. None of the above
5. T/F once activated receptor tyrosine kinases start to phosphorylate themselves
6. What is the MAP-kinase pathway?
a. RTK
b. RAS
c. MAPKKK
d. MAPKK
e. MAPK
f. Protein activity or gene expression
7. The MAP-kinase pathway often stimulates
a. Apoptosis
b. Necrosis
c. Cell proliferation and survival
d. Two of these
8. Chromosomes are X shaped during
a. Meiosis
b. Mitosis
c. Apoptosis
d. Necrosis
9. Cyclin and CDKs come together to proteins to drive the cell cycle forward
a. Dephosphorylate
b. Phosphorylate
c. Dehydrogenate
, d. Hydrogenate
10. T/F each phase of the cell cycle uses the same cyclin/CDK complex
11. How can the cyclin/CDK complex be turned off to prevent cancer
a. Methylation
b. Acetylation
c. Ubiquitination (cyclin degraded, CDK recycled)
d. All of these
12. When 2 phosphates are attached to the cyclin/CDK complex it is
a. Active
b. Inactive
13. What kinds of cells spend most, if not all, of their time in the G0 phase?
a. Skin cells
b. Gut cells
c. Sperm cells
d. Neurons
14. What happens during s-phase?
a. synthesizing/replicating DNA
15. During s phase, the number of chromosomes , while the amount of genetic
material .
a. Stays the same, doubles
b. Doubles, stays the same
c. Quadruples, doubles
d. Doubles, quadruples
16. These structures hold the sister chromatids in place so they dont break off during
replication
a. Actin contractile rings
b. Condensin rings
c. Cohesin rings
d. Epoxide rings
e. Two of the above
f. None of the above
17. Which of these genetic diseases could occur if there was an error in the cohesin rings?
a. Cystic fibrosis
b. Down syndrome (trisomy 21)
c. Beta-thalassemia
d. Sickle cell anemia
18. These structures help condense chromatin for M-phase
a. Actin contractile rings
b. Condensin rings
c. Cohesin rings
d. Epoxide rings
e. Two of the above
f. None of the above
19. Which of these is in correct order
1. Activated activates PLC which then activates .
a. G-protein, DAG
b. G-protein, calcium
c. G-protein, IP3
d. Two of the above the g-protein activates PLC which activates IP3 and DAG
e. None of the above
2. What does IP3 activate? What does this cause?
a. IP3 binds to calcium channels, allowing calcium to release from the ER. An
example of this is when sperm goes into the egg, it causes a release of
calcium which turns the embryo “on” starting life.
3. Once calcium is released in the PLC pathway, it binds to which changes its
shape so it can become an effector protein to activate other proteins
a. Cyclic AMP
b. Calmodulin
c. Receptor tyrosine kinase
d. Two of these
e. None of these
4. Which type of pathway is responsible for vision (superfast pathway)
a. GPCR pathway
b. Ion channel pathway
c. Enzyme coupled receptor pathway
d. None of the above
5. T/F once activated receptor tyrosine kinases start to phosphorylate themselves
6. What is the MAP-kinase pathway?
a. RTK
b. RAS
c. MAPKKK
d. MAPKK
e. MAPK
f. Protein activity or gene expression
7. The MAP-kinase pathway often stimulates
a. Apoptosis
b. Necrosis
c. Cell proliferation and survival
d. Two of these
8. Chromosomes are X shaped during
a. Meiosis
b. Mitosis
c. Apoptosis
d. Necrosis
9. Cyclin and CDKs come together to proteins to drive the cell cycle forward
a. Dephosphorylate
b. Phosphorylate
c. Dehydrogenate
, d. Hydrogenate
10. T/F each phase of the cell cycle uses the same cyclin/CDK complex
11. How can the cyclin/CDK complex be turned off to prevent cancer
a. Methylation
b. Acetylation
c. Ubiquitination (cyclin degraded, CDK recycled)
d. All of these
12. When 2 phosphates are attached to the cyclin/CDK complex it is
a. Active
b. Inactive
13. What kinds of cells spend most, if not all, of their time in the G0 phase?
a. Skin cells
b. Gut cells
c. Sperm cells
d. Neurons
14. What happens during s-phase?
a. synthesizing/replicating DNA
15. During s phase, the number of chromosomes , while the amount of genetic
material .
a. Stays the same, doubles
b. Doubles, stays the same
c. Quadruples, doubles
d. Doubles, quadruples
16. These structures hold the sister chromatids in place so they dont break off during
replication
a. Actin contractile rings
b. Condensin rings
c. Cohesin rings
d. Epoxide rings
e. Two of the above
f. None of the above
17. Which of these genetic diseases could occur if there was an error in the cohesin rings?
a. Cystic fibrosis
b. Down syndrome (trisomy 21)
c. Beta-thalassemia
d. Sickle cell anemia
18. These structures help condense chromatin for M-phase
a. Actin contractile rings
b. Condensin rings
c. Cohesin rings
d. Epoxide rings
e. Two of the above
f. None of the above
19. Which of these is in correct order
