MEDICINAL
MEDICINAL Etf 3- Define these four components.
(1) the processing phase of the
substance before it gets to the
systemic circulation.
1- what is the difference between PK
and PD ?
(2) the distribution through
fluids and tissues
* Pharmacokinetics describes
how the drug conc. changes as it
get distributed through out the (3) irreversible transformation
body— how the body affects the of the substance into smaller
drug polar molecules.
* Pharmacodynamics studies
(4) the clearance, in which the
the way the drug function on
substance exits the body
the body through different
mechanisms
2- what are the 4 major 4- Where each steps occur
components of PK ? in the body ?
- Absorption (1) - depends on the route of
administration
- Distribution (2) Vascular space (blood/ plasma)
- Metabolism (3) = Main site: Liver
- Excretion (4) -
Kidney
Name: Qabas Mansour
MEDICINAL Etf 3- Define these four components.
(1) the processing phase of the
substance before it gets to the
systemic circulation.
1- what is the difference between PK
and PD ?
(2) the distribution through
fluids and tissues
* Pharmacokinetics describes
how the drug conc. changes as it
get distributed through out the (3) irreversible transformation
body— how the body affects the of the substance into smaller
drug polar molecules.
* Pharmacodynamics studies
(4) the clearance, in which the
the way the drug function on
substance exits the body
the body through different
mechanisms
2- what are the 4 major 4- Where each steps occur
components of PK ? in the body ?
- Absorption (1) - depends on the route of
administration
- Distribution (2) Vascular space (blood/ plasma)
- Metabolism (3) = Main site: Liver
- Excretion (4) -
Kidney
Name: Qabas Mansour